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APLS vs MRK

APLS
Apellis Pharmaceuticals, Inc.
BEARISH
Price
$18.94
Market Cap
$2.42B
Sector
Healthcare
AI Confidence
85%
MRK
Merck & Co., Inc.
NEUTRAL
Price
$121.25
Market Cap
$299.79B
Sector
Healthcare
AI Confidence
90%

Valuation

P/E Ratio
APLS
105.22
MRK
16.66
Forward P/E
APLS
-77.94
MRK
12.42
P/B Ratio
APLS
6.48
MRK
5.7
P/S Ratio
APLS
2.41
MRK
4.61
EV/EBITDA
APLS
42.6
MRK
11.46

Profitability

Gross Margin
APLS
60.34%
MRK
77.21%
Operating Margin
APLS
-25.58%
MRK
32.77%
Profit Margin
APLS
2.23%
MRK
28.08%
ROE
APLS
7.48%
MRK
36.88%
ROA
APLS
3.53%
MRK
12.04%

Growth

Revenue Growth
APLS
-5.9%
MRK
5.0%
Earnings Growth
APLS
--
MRK
-19.3%

Financial Health

Debt/Equity
APLS
1.28
MRK
0.96
Current Ratio
APLS
3.14
MRK
1.54
Quick Ratio
APLS
2.59
MRK
0.96

Dividends

Dividend Yield
APLS
--
MRK
2.83%
Payout Ratio
APLS
0.0%
MRK
45.05%

AI Verdict

APLS BEARISH

APLS exhibits weak financial health per the Piotroski F-Score of 4/9, indicating a fragile foundation despite some positive gross margins and cash reserves. The company is unprofitable with negative operating margins and declining revenue, while insider selling activity and a bearish technical trend signal pessimism. Although the Graham Number ($3.44) and intrinsic value ($1.26) suggest deep undervaluation, the current price of $18.94 reflects high growth expectations that are not supported by fundamentals. The absence of an Altman Z-Score raises concern about default risk, especially given a debt/equity ratio of 1.28 and negative earnings. Analysts recommend 'buy' with a target of $33.60, but this optimism appears disconnected from deteriorating operational and financial trends.

Strengths
High gross margin of 60.34% indicates strong pricing power or low production costs
Current ratio of 3.14 and quick ratio of 2.59 suggest strong short-term liquidity
Positive earnings surprises in 2 out of the last 4 quarters (average +29.25%) show potential for upside in earnings execution
Risks
Piotroski F-Score of 4/9 indicates weak financial health and deteriorating fundamentals
Negative operating margin (-25.58%) and declining revenue (YoY -5.90%) signal ongoing operational inefficiencies
Insiders sold $1.47M worth of shares in the last 6 months with no buys, signaling lack of confidence
MRK NEUTRAL

MRK shows neutral fundamentals based on deterministic rules. Financial strength is weak (F-Score 3/9). Mixed signals with both opportunities and risks present.

Strengths
Strong profitability (28.1% margin)
Strong ROE of 36.9%
Risks
Premium vs Graham Number ($59.01)
Weak financial trend (Piotroski F-Score: 3/9)

Compare Another Pair

APLS vs MRK: Head-to-Head Comparison

This page compares Apellis Pharmaceuticals, Inc. (APLS) and Merck & Co., Inc. (MRK) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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