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BCYC vs DNA

BCYC
Bicycle Therapeutics plc
BEARISH
Price
$6.95
Market Cap
$482.1M
Sector
Healthcare
AI Confidence
68%
DNA
Ginkgo Bioworks Holdings, Inc.
BEARISH
Price
$7.87
Market Cap
$487.3M
Sector
Healthcare
AI Confidence
95%

Valuation

P/E Ratio
BCYC
--
DNA
--
Forward P/E
BCYC
-1.99
DNA
-2.17
P/B Ratio
BCYC
0.78
DNA
0.9
P/S Ratio
BCYC
17.01
DNA
2.86
EV/EBITDA
BCYC
0.57
DNA
-1.77

Profitability

Gross Margin
BCYC
0.0%
DNA
72.39%
Operating Margin
BCYC
-558.64%
DNA
-209.74%
Profit Margin
BCYC
0.0%
DNA
-183.81%
ROE
BCYC
-34.59%
DNA
-51.08%
ROA
BCYC
-20.59%
DNA
-15.42%

Growth

Revenue Growth
BCYC
338.5%
DNA
-23.8%
Earnings Growth
BCYC
--
DNA
--

Financial Health

Debt/Equity
BCYC
0.01
DNA
0.86
Current Ratio
BCYC
10.66
DNA
4.92
Quick Ratio
BCYC
10.33
DNA
4.66

Dividends

Dividend Yield
BCYC
--
DNA
--
Payout Ratio
BCYC
0.0%
DNA
0.0%

AI Verdict

BCYC BEARISH

The Advanced Deterministic Scorecard reveals a weak financial health profile with a Piotroski F-Score of 4/9, indicating borderline stability, and no available Altman Z-Score prevents a full distress risk assessment. Despite a remarkable 338.5% year-over-year revenue growth and strong analyst target price of $21.50 implying 210% upside, the company continues to report deep operating losses (-558.64% operating margin), deteriorating earnings (YoY EPS growth of -18.1%), and inconsistent earnings surprises, with only 1 out of the last 4 quarters beating estimates. High valuation multiples (Price/Sales of 17.01) contrast with negative profitability and weak insider sentiment, while recent insider selling adds downward pressure. Although the balance sheet appears strong with a current ratio of 10.66 and minimal debt, the lack of profitability and cash flow transparency limits confidence in sustainable recovery.

Strengths
Exceptional year-over-year revenue growth of 338.50% suggests strong commercial or partnership momentum
Exceptionally strong liquidity position with current ratio of 10.66 and quick ratio of 10.33
Very low leverage with Debt/Equity ratio of just 0.01, reducing financial risk
Risks
Piotroski F-Score of 4 indicates weak financial health and limited operational strength
Operating margin of -558.64% reflects severe unprofitability and cost inefficiency
Negative ROE (-34.59%) and negative ROA (-20.59%) demonstrate poor capital utilization
DNA BEARISH

The deterministic health profile is critical, highlighted by a Piotroski F-Score of 1/9, indicating severe financial distress and operational deterioration. Despite a strong current ratio of 4.92 providing a short-term liquidity buffer, the company is facing a systemic collapse in growth with YoY revenue declining by 23.80%. Massive negative operating margins (-209.74%) and a catastrophic 5-year price decline of 98.1% suggest a failing business model. The combination of shrinking top-line revenue and bearish insider selling confirms a high-risk profile.

Strengths
High liquidity with a Current Ratio of 4.92
Strong Gross Margin of 72.39% indicating core product value
Trading slightly below book value (P/B 0.90)
Risks
Severe financial instability (Piotroski F-Score 1/9)
Negative revenue growth (-23.80% YoY) indicating loss of market traction
Extreme cash burn with an operating margin of -209.74%

Compare Another Pair

BCYC vs DNA: Head-to-Head Comparison

This page compares Bicycle Therapeutics plc (BCYC) and Ginkgo Bioworks Holdings, Inc. (DNA) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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