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GRFS vs PTGX

GRFS
Grifols, S.A.
NEUTRAL
Price
$8.21
Market Cap
$6.74B
Sector
Healthcare
AI Confidence
80%
PTGX
Protagonist Therapeutics, Inc.
NEUTRAL
Price
$105.98
Market Cap
$6.76B
Sector
Healthcare
AI Confidence
80%

Valuation

P/E Ratio
GRFS
12.83
PTGX
--
Forward P/E
GRFS
5.64
PTGX
-244.06
P/B Ratio
GRFS
0.92
PTGX
10.79
P/S Ratio
GRFS
0.9
PTGX
146.96
EV/EBITDA
GRFS
9.85
PTGX
-39.56

Profitability

Gross Margin
GRFS
38.8%
PTGX
100.0%
Operating Margin
GRFS
17.53%
PTGX
-677.09%
Profit Margin
GRFS
5.34%
PTGX
-282.83%
ROE
GRFS
6.17%
PTGX
-20.18%
ROA
GRFS
4.24%
PTGX
-13.99%

Growth

Revenue Growth
GRFS
0.3%
PTGX
-95.6%
Earnings Growth
GRFS
43.5%
PTGX
--

Financial Health

Debt/Equity
GRFS
1.27
PTGX
0.02
Current Ratio
GRFS
2.51
PTGX
12.71
Quick Ratio
GRFS
0.84
PTGX
12.59

Dividends

Dividend Yield
GRFS
2.14%
PTGX
--
Payout Ratio
GRFS
27.5%
PTGX
0.0%

AI Verdict

GRFS NEUTRAL

GRFS presents a classic 'value trap' profile: strong deterministic health (Piotroski F-Score 7/9) and deep valuation discounts (Price < Graham Number < Intrinsic Value), yet it suffers from severe market rejection. While the stock trades at a significant discount to its Graham Number of $11.36 and Intrinsic Value of $18.88, this is offset by a 0/100 technical trend and a dismal earnings track record with 0 beats in the last 4 quarters. The disconnect between strong operational health scores and poor price performance suggests systemic risks or lack of catalyst for a reversal.

Strengths
Strong Piotroski F-Score (7/9) indicating improving operational efficiency
Deep value valuation with P/B (0.92) and P/S (0.90) both under 1.0
Significant upside to Graham Number ($11.36) and Intrinsic Value ($18.88)
Risks
Severe earnings miss trend (Average surprise -27.42% over last 4 quarters)
Stagnant top-line growth (Revenue growth YoY only 0.30%)
Bearish technical momentum (Technical Trend score 0/100)
PTGX NEUTRAL

PTGX exhibits a strong deterministic health profile with a Piotroski F-Score of 7/9 and a fortress-like balance sheet (Current Ratio 12.71, Debt/Equity 0.02). However, the company is in a speculative pre-commercial phase, evidenced by a staggering Price/Sales ratio of 146.96 and negative profit margins. While analysts maintain a 'strong_buy' based on the late-stage pipeline (Icotyde and Rusfertide), significant insider selling by the CEO and CFO creates a divergence between institutional optimism and internal sentiment.

Strengths
Strong Piotroski F-Score (7/9) indicating improving financial health
Exceptional liquidity with a Current Ratio of 12.71
Negligible debt levels (Debt/Equity 0.02)
Risks
Binary regulatory risk associated with FDA/EMA approval of Icotyde and Rusfertide
Extreme valuation premiums (P/S 146.96, P/B 10.79)
Severe revenue volatility (-95.6% YoY) typical of milestone-based biotech

Compare Another Pair

GRFS vs PTGX: Head-to-Head Comparison

This page compares Grifols, S.A. (GRFS) and Protagonist Therapeutics, Inc. (PTGX) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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