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HRTX vs SPRO

HRTX
Heron Therapeutics, Inc.
BEARISH
Price
$0.85
Market Cap
$160.8M
Sector
Healthcare
AI Confidence
85%
SPRO
Spero Therapeutics, Inc.
BEARISH
Price
$2.75
Market Cap
$159.2M
Sector
Healthcare
AI Confidence
85%

Valuation

P/E Ratio
HRTX
--
SPRO
18.33
Forward P/E
HRTX
1.67
SPRO
-2.48
P/B Ratio
HRTX
12.01
SPRO
2.63
P/S Ratio
HRTX
1.04
SPRO
2.38
EV/EBITDA
HRTX
-1142.32
SPRO
17.01

Profitability

Gross Margin
HRTX
72.64%
SPRO
42.42%
Operating Margin
HRTX
0.09%
SPRO
76.05%
Profit Margin
HRTX
-13.04%
SPRO
12.83%
ROE
HRTX
--
SPRO
16.3%
ROA
HRTX
-0.65%
SPRO
4.99%

Growth

Revenue Growth
HRTX
-0.5%
SPRO
174.5%
Earnings Growth
HRTX
--
SPRO
--

Financial Health

Debt/Equity
HRTX
9.81
SPRO
0.05
Current Ratio
HRTX
2.48
SPRO
7.59
Quick Ratio
HRTX
1.42
SPRO
7.4

Dividends

Dividend Yield
HRTX
--
SPRO
--
Payout Ratio
HRTX
0.0%
SPRO
0.0%

AI Verdict

HRTX BEARISH

HRTX presents a high-risk profile characterized by a stable but mediocre Piotroski F-Score of 4/9 and a complete lack of positive technical momentum (0/100). While the company maintains strong gross margins (72.64%) and a healthy current ratio (2.48), these are overshadowed by an extreme Debt/Equity ratio of 9.81 and a catastrophic 5-year price decline of 94.8%. There is a severe disconnect between the 'Strong Buy' analyst consensus with a $4.33 target and the actual market performance and fundamental leverage.

Strengths
Strong Gross Margin of 72.64%
Healthy liquidity with a Current Ratio of 2.48
Operating margin is near break-even (0.09%)
Risks
Extreme leverage with Debt/Equity at 9.81
Severe long-term value destruction (5Y Change: -94.8%)
Stagnant revenue growth (-0.50% YoY)
SPRO BEARISH

SPRO exhibits a critical divergence between its explosive revenue growth and its underlying financial health, evidenced by a weak Piotroski F-Score of 2/9. While the company maintains a strong current ratio (7.59) and low debt, the current price of $2.75 trades at a significant premium to both its Graham Number ($1.88) and Intrinsic Value ($1.05). This valuation gap, combined with aggressive insider selling by the CEO and COO and a bearish technical trend, suggests the recent 1-year price surge is unsustainable. The negative forward P/E further indicates an expectation of returning to losses despite recent revenue spikes.

Strengths
Exceptional YoY revenue growth of 174.50%
Very high liquidity with a current ratio of 7.59
Minimal leverage with a Debt/Equity ratio of 0.05
Risks
Severe financial health deterioration indicated by Piotroski F-Score (2/9)
Strong bearish insider signal with multiple sales by CEO and COO
Significant overvaluation relative to Graham and Intrinsic value baselines

Compare Another Pair

HRTX vs SPRO: Head-to-Head Comparison

This page compares Heron Therapeutics, Inc. (HRTX) and Spero Therapeutics, Inc. (SPRO) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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