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INSM vs ONC

INSM
Insmed Incorporated
BEARISH
Price
$154.81
Market Cap
$33.42B
Sector
Healthcare
AI Confidence
85%
ONC
BeOne Medicines AG
NEUTRAL
Price
$319.94
Market Cap
$36.75B
Sector
Healthcare
AI Confidence
85%

Valuation

P/E Ratio
INSM
--
ONC
124.98
Forward P/E
INSM
211.7
ONC
34.45
P/B Ratio
INSM
44.89
ONC
8.13
P/S Ratio
INSM
55.1
ONC
6.88
EV/EBITDA
INSM
-33.34
ONC
791.24

Profitability

Gross Margin
INSM
79.73%
ONC
87.49%
Operating Margin
INSM
-94.64%
ONC
12.35%
Profit Margin
INSM
-210.54%
ONC
5.37%
ROE
INSM
-249.28%
ONC
7.46%
ROA
INSM
-28.99%
ONC
3.96%

Growth

Revenue Growth
INSM
152.6%
ONC
32.8%
Earnings Growth
INSM
--
ONC
--

Financial Health

Debt/Equity
INSM
1.01
ONC
0.25
Current Ratio
INSM
3.83
ONC
3.41
Quick Ratio
INSM
3.35
ONC
2.97

Dividends

Dividend Yield
INSM
--
ONC
--
Payout Ratio
INSM
0.0%
ONC
0.0%

AI Verdict

INSM BEARISH

Insmed Incorporated exhibits a weak deterministic health profile with a Piotroski F-Score of 3/9, indicating significant fundamental instability. While the company shows explosive revenue growth of 152.6%, this is offset by extreme valuation metrics (Price/Sales of 55.10) and a consistent track record of missing earnings estimates (0/4 beats in the last year). The stark disconnect between the 'Strong Buy' analyst consensus and the bearish insider activity—including significant sales by the CEO and COO—suggests a high-risk speculative profile rather than a value-driven investment.

Strengths
Hyper-growth revenue increase of 152.60% YoY
Strong gross margins of 79.73% typical of high-value biotech
Robust short-term liquidity with a current ratio of 3.83
Risks
Extreme valuation with a Forward P/E of 211.70 and P/S of 55.10
Severe lack of profitability with a profit margin of -210.54%
Chronic failure to meet earnings expectations (0/4 recent beats)
ONC NEUTRAL

ONC exhibits strong operational health with a Piotroski F-Score of 7/9 and a robust balance sheet characterized by low debt (D/E 0.25) and high liquidity. However, there is a severe disconnect between the current market price ($319.94) and deterministic value metrics, with the Graham Number ($47.6) and Intrinsic Value ($17.92) suggesting massive overvaluation. While the company has successfully transitioned from deep historical losses to profitability and maintains strong revenue growth (32.8%), aggressive insider selling by the CEO and a bearish technical trend offset the 'Strong Buy' analyst consensus.

Strengths
Strong financial health (Piotroski F-Score 7/9)
Excellent liquidity with a Current Ratio of 3.41
High gross margins (87.49%) typical of high-value biotech
Risks
Extreme valuation premium (P/E 124.98 vs. Intrinsic Value $17.92)
Bearish insider sentiment with significant CEO divestment
High volatility in quarterly earnings surprises

Compare Another Pair

INSM vs ONC: Head-to-Head Comparison

This page compares Insmed Incorporated (INSM) and BeOne Medicines AG (ONC) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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