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IONS vs LLY

IONS
Ionis Pharmaceuticals, Inc.
BEARISH
Price
$75.17
Market Cap
$12.42B
Sector
Healthcare
AI Confidence
85%
LLY
Eli Lilly and Company
NEUTRAL
Price
$958.65
Market Cap
$858.01B
Sector
Healthcare
AI Confidence
85%

Valuation

P/E Ratio
IONS
--
LLY
41.7
Forward P/E
IONS
-120.83
LLY
22.78
P/B Ratio
IONS
25.1
LLY
32.33
P/S Ratio
IONS
13.16
LLY
13.16
EV/EBITDA
IONS
-33.45
LLY
27.08

Profitability

Gross Margin
IONS
1.29%
LLY
83.04%
Operating Margin
IONS
-105.47%
LLY
44.9%
Profit Margin
IONS
-40.41%
LLY
31.67%
ROE
IONS
-70.8%
LLY
101.16%
ROA
IONS
-7.31%
LLY
19.41%

Growth

Revenue Growth
IONS
-10.3%
LLY
42.6%
Earnings Growth
IONS
--
LLY
51.4%

Financial Health

Debt/Equity
IONS
5.35
LLY
1.65
Current Ratio
IONS
3.83
LLY
1.58
Quick Ratio
IONS
3.51
LLY
0.78

Dividends

Dividend Yield
IONS
--
LLY
0.68%
Payout Ratio
IONS
0.0%
LLY
26.14%

AI Verdict

IONS BEARISH

IONS presents a significant disconnect between its market valuation and fundamental performance. While the Piotroski F-Score of 5/9 indicates stable financial health, the company is grappling with negative revenue growth (-10.30%) and a severe collapse in YoY EPS (-167.4%). Despite a massive 181% price surge over the last year, the valuation is extreme with a Price/Book of 25.10 and a Price/Sales of 13.16. Heavy insider selling by the CEO and CFO, combined with a bearish technical trend, suggests the current price is driven by speculative pipeline expectations rather than realized value.

Strengths
Strong short-term liquidity with a Current Ratio of 3.83
Consistent history of beating earnings estimates (3 of last 4 quarters)
Strong analyst consensus with a target price of $97.60
Risks
Extreme valuation premiums (P/B 25.10, P/S 13.16)
Negative revenue growth (-10.30% YoY) and declining Q/Q revenue
Severe profitability issues with an operating margin of -105.47%
LLY NEUTRAL

LLY shows neutral fundamentals based on deterministic rules. Financial strength is weak (F-Score 3/9). Mixed signals with both opportunities and risks present.

Strengths
Strong profitability (31.7% margin)
Strong revenue growth of 42.6%
Strong ROE of 101.2%
Risks
High valuation with P/E of 41.7
Premium vs Graham Number ($123.85)
Weak financial trend (Piotroski F-Score: 3/9)

Compare Another Pair

IONS vs LLY: Head-to-Head Comparison

This page compares Ionis Pharmaceuticals, Inc. (IONS) and Eli Lilly and Company (LLY) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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