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IRWD vs LYEL

IRWD
Ironwood Pharmaceuticals, Inc.
BEARISH
Price
$3.63
Market Cap
$591.9M
Sector
Healthcare
AI Confidence
85%
LYEL
Lyell Immunopharma, Inc.
BEARISH
Price
$24.80
Market Cap
$578.5M
Sector
Healthcare
AI Confidence
85%

Valuation

P/E Ratio
IRWD
24.2
LYEL
--
Forward P/E
IRWD
2.49
LYEL
-29.52
P/B Ratio
IRWD
-2.26
LYEL
2.12
P/S Ratio
IRWD
2.0
LYEL
16070.7
EV/EBITDA
IRWD
8.08
LYEL
-2.06

Profitability

Gross Margin
IRWD
67.88%
LYEL
100.0%
Operating Margin
IRWD
13.73%
LYEL
-1024630.0%
Profit Margin
IRWD
8.11%
LYEL
0.0%
ROE
IRWD
--
LYEL
-86.98%
ROA
IRWD
19.85%
LYEL
-29.83%

Growth

Revenue Growth
IRWD
-47.3%
LYEL
-45.5%
Earnings Growth
IRWD
--
LYEL
--

Financial Health

Debt/Equity
IRWD
--
LYEL
0.21
Current Ratio
IRWD
1.13
LYEL
5.28
Quick Ratio
IRWD
1.08
LYEL
5.0

Dividends

Dividend Yield
IRWD
--
LYEL
--
Payout Ratio
IRWD
0.0%
LYEL
0.0%

AI Verdict

IRWD BEARISH

Ironwood Pharmaceuticals presents a high-risk profile characterized by a stable but mediocre Piotroski F-Score of 4/9 and a critical lack of equity, as evidenced by a negative Price/Book ratio of -2.26. While the stock has seen a massive 1-year price surge, this is fundamentally unsupported by a 47.3% collapse in year-over-year revenue and a significant disconnect between the current price ($3.63) and the growth-based intrinsic value ($1.05). Heavy insider selling totaling nearly $22 million further signals a lack of confidence from company leadership.

Strengths
Strong gross margins (67.88%)
Positive operating margin (13.73%)
Recent 1-year price momentum (+259.4%)
Risks
Negative shareholders' equity (Price/Book: -2.26)
Severe revenue contraction (-47.3% YoY)
Significant overvaluation relative to intrinsic value ($3.63 vs $1.05)
LYEL BEARISH

LYEL exhibits critical financial weakness, highlighted by a Piotroski F-Score of 1/9, indicating severe deterioration in fundamental health. Despite a speculative 1-year price rally of 178.7%, the company suffers from extreme operating losses (-1,024,633% margin) and negative revenue growth (-45.50%). The valuation is disconnected from fundamentals, evidenced by an astronomical Price/Sales ratio, while insider sentiment remains bearish with consistent selling by top executives.

Strengths
Strong short-term liquidity with a Current Ratio of 5.28
Low leverage with a Debt/Equity ratio of 0.21
Positive analyst sentiment with a mean target price of $34.80
Risks
Critical financial health as indicated by a 1/9 Piotroski F-Score
Extreme cash burn and negative operating margins
Negative revenue growth (-45.50% YoY) and EPS contraction

Compare Another Pair

IRWD vs LYEL: Head-to-Head Comparison

This page compares Ironwood Pharmaceuticals, Inc. (IRWD) and Lyell Immunopharma, Inc. (LYEL) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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