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CANF

BEARISH
$2.91 Live
Can-Fite BioPharma Ltd. · AMEX
Target $50.0 (+1618.2%)
$2.87 52W Range $24.0

At a glance

Key valuation, profitability, growth, and risk metrics.

Updated Apr 25, 2026
Market cap
$6.23M
P/E
N/A
ROE
-178.2%
Profit margin
N/A
Debt/Equity
0.01
Dividend yield
N/A

AI Analysis

AI-powered fundamental assessment

Confidence
95%
CANF presents a profile of a failing micro-cap biotechnology firm, characterized by a Piotroski F-Score of 5/9 which suggests baseline stability but masks severe operational decay. While the balance sheet remains liquid with a Current Ratio of 3.46 and negligible debt, the company is experiencing a catastrophic collapse in market value (-99.4% over 5 years) and a significant decline in revenue (-43.3% YoY). The extreme negative operating margin of -2488.67% indicates an unsustainable burn rate that outweighs the benefit of trading below book value (P/B 0.68).

Key Strengths

Very low Debt/Equity ratio (0.01)
Strong short-term liquidity (Current Ratio 3.46)
Trading below book value (P/B 0.68)
High gross margins (100%) typical of early-stage R&D
Stable Piotroski F-Score (5/9) relative to peer biotech volatility

Key Risks

Severe revenue contraction (-43.3% YoY)
Extreme operational inefficiency (Operating Margin -2488.67%)
Catastrophic long-term price performance (-99.4% 5Y change)
Micro-cap liquidity risk (Market Cap $0.01B)
Lack of consistent earnings and high volatility in EPS surprises
AI Fair Value Estimate
Based on comprehensive analysis
$3.1
+6.5% above current price

Performance Snowflake

Multi-dimensional analysis across 5 key categories

Overall
22
Weak
Value
35
Future
10
Past
5
Health
60
Dividend
0
AI Verdict
High-Risk Speculative
Key drivers: Revenue decline, Extreme operating losses, Price trend collapse, Micro-cap status
Confidence
90%
Value
35/100

Ref P/E N/A, P/B 0.68, P/S 15.39

Positives
  • P/B ratio of 0.68 suggests the stock is undervalued relative to assets
Watchpoints
  • P/S ratio of 15.39 is excessively high for a company with shrinking revenue
  • No Graham Number available due to lack of earnings
Future
10/100

Ref Revenue Growth -43.30%

Positives
  • Single analyst target price of $50.00 suggests extreme upside potential if a clinical breakthrough occurs
Watchpoints
  • Revenue growth is deeply negative (-43.3%)
  • Forward P/E is negative
Past
5/100

Ref 5Y Change -99.4%

Positives
No standout positives identified.
Watchpoints
  • 5-year price change of -99.4%
  • Consistent history of missing earnings estimates by wide margins
Health
60/100

Ref Piotroski 5/9, Debt/Equity 0.01

Positives
  • Piotroski F-Score of 5/9 is stable
  • Debt/Equity is nearly zero
  • Quick Ratio of 3.13 is healthy
Watchpoints
  • ROE is deeply negative (-178.24%)
Dividend
0/100

Ref Dividend Yield N/A

Positives
No standout positives identified.
Watchpoints
  • No dividend history
  • Zero payout ratio

Stock Price & Analyst Targets

Real-time price movements and analyst price targets

Current Price
$2.91
Analyst Target
$50.0
Upside/Downside
+1618.2%

Multi-Horizon Performance vs Peers

Price momentum across 5Y → 1W horizons for CANF and closest competitors.

Updated 2026-04-24
CAN
Can-Fite BioPharma Ltd.
Primary
5Y
-99.4%
3Y
-91.8%
1Y
-87.6%
6M
-68.4%
1M
-9.9%
1W
-4.3%
QUC
Mainz Biomed N.V.
Peer
5Y
-98.2%
3Y
-91.0%
1Y
-84.9%
6M
-67.3%
1M
-19.4%
1W
+9.9%
BRT
BioRestorative Therapies, Inc.
Peer
5Y
-99.5%
3Y
-93.0%
1Y
-85.2%
6M
-84.5%
1M
+8.1%
1W
-7.9%
BIA
bioAffinity Technologies, Inc.
Peer
5Y
-99.5%
3Y
-98.4%
1Y
-92.9%
6M
-86.5%
1M
+9.8%
1W
-1.5%
NXG
NEXGEL, Inc.
Peer
5Y
-78.5%
3Y
-49.8%
1Y
-73.0%
6M
-70.1%
1M
-8.6%
1W
+18.5%

Positive values indicate cumulative gains over the specified period. Comparables pulled from the same sector to highlight whether momentum is stock-specific or industry-wide.

Historical Performance Trends

Long-term financial metrics and growth patterns

Revenue & Net Income

Profit & Operating Margins

Return on Equity (ROE)

Quarterly Revenue Growth

Historical data shows last 12 quarters (3 years)

Valuation Metrics

Key valuation ratios and pricing indicators

P/E Ratio
N/A
Forward P/E
-3.99
PEG Ratio
N/A
P/B Ratio
0.68
P/S Ratio
15.39
EV/Revenue
9.88
EV/EBITDA
-0.4
Market Cap
$6.23M

Profitability

Profit margins and return metrics

Profit Margin N/A
Operating Margin -2488.67%
Gross Margin 100.0%
ROE -178.24%
ROA -66.75%

Growth

Revenue and earnings growth rates

Revenue Growth -43.3%
Earnings Growth N/A
Q/Q Revenue Growth N/A
Q/Q Earnings Growth N/A

Financial Health

Balance sheet strength and liquidity metrics

Debt/Equity
0.01
Low debt
Current Ratio
3.46
Strong
Quick Ratio
3.13
Excellent
Cash/Share
$1.99

Financial Statement Flow

Interactive flow visualization showing how money moves through the company Q4 2025

Total Assets
$0.0B
Liabilities
$0.0B
Equity
$0.0B
Debt/Equity
0.70x

Quarterly Earnings History

EPS performance vs analyst estimates

2025-08-28
$N/A
+100.0% surprise
2024-03-28
$-60.0
-710.8% surprise
2023-11-30
$N/A
+100.0% surprise
2023-08-31
$N/A
+100.0% surprise

Healthcare Sector Comparison

Comparing CANF against 536 companies in the Healthcare sector (28 bullish, 158 neutral, 350 bearish)
Return on Equity (ROE)
-178.24%
This Stock
vs
-92.06%
Sector Avg
+93.6% (Excellent)
Debt to Equity
0.01
This Stock
vs
2.73
Sector Avg
-99.5% (Less Debt)
Revenue Growth
-43.3%
This Stock
vs
129.68%
Sector Avg
-133.4% (Slower)
Current Ratio
3.46
This Stock
vs
4.57
Sector Avg
-24.4% (Weaker)

Similar Companies

Peer comparison within the same industry

SEC Filings

Recent regulatory filings from the SEC EDGAR database

20-F
ANNUAL REPORT
2026-03-26

CANF filed its annual report on Form 20-F on March 26, 2026. Specific financial highlights and risk factors were not provided in the available metadata.

20-F
ANNUAL REPORT
2025-04-14

CANF filed its annual report on Form 20-F on April 14, 2025. Due to the limited information provided, specific financial highlights and risk factors are not available for summary.

Data sourced from SEC EDGAR. AI summaries generated automatically.

Wall Street Analysts

Professional analyst ratings and price targets

Consensus
NONE
1 analysts
D. Boral Capital
2025-12-24
down
Buy Hold
D. Boral Capital
2025-12-17
Maintains
Buy Buy
D. Boral Capital
2025-11-18
Maintains
Buy Buy

Past News Coverage

Recent headlines mentioning CANF from our newsroom.

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