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LCTX

BEARISH
$1.56 Live
Lineage Cell Therapeutics, Inc. · AMEX
Target $4.5 (+188.5%)
$0.43 52W Range $2.09

At a glance

Key valuation, profitability, growth, and risk metrics.

Updated Apr 29, 2026
Market cap
$388.58M
P/E
N/A
ROE
-105.3%
Profit margin
N/A
Debt/Equity
0.06
Dividend yield
N/A

AI Analysis

AI-powered fundamental assessment

Confidence
85%
LCTX exhibits severe financial distress as evidenced by a Piotroski F-Score of 1/9, indicating critical weakness across nearly all fundamental health dimensions. While the company maintains a strong liquidity position with a current ratio of 5.20 and low debt, it suffers from negative gross margins (-22.80%) and an unsustainable operating margin of -99.09%. The valuation is extreme, with a Price/Sales ratio of 26.70 and a PEG of 10.64, suggesting the stock is priced for perfection despite consistent earnings misses. The stark contrast between the 'Strong Buy' analyst consensus and the deterministic health scores suggests a speculative bet on clinical outcomes rather than a value-driven investment.

Key Strengths

Strong short-term liquidity with a current ratio of 5.20
Very low leverage with a Debt/Equity ratio of 0.06
Significant year-over-year revenue growth of 130.40%
Strong analyst support with a target price of $4.50
Positive 1-year price momentum (+239.1%)

Key Risks

Critical fundamental health (Piotroski F-Score 1/9)
Negative gross margins indicating a non-viable current cost structure
Extreme valuation multiples (P/S 26.70, P/B 8.52)
Consistent failure to meet earnings estimates (Avg surprise -204.63% last 4 quarters)
High cash burn rate reflected in -99.09% operating margin

Performance Snowflake

Multi-dimensional analysis across 5 key categories

Overall
18
Weak
Value
10
Future
45
Past
20
Health
15
Dividend
0
AI Verdict
Speculative/High Risk
Key drivers: Piotroski F-Score 1/9, Negative Gross Margins, High Liquidity, Extreme P/S Ratio
Confidence
90%
Value
10/100

No Graham Number available due to lack of earnings; valuation is purely speculative.

Positives
No standout positives identified.
Watchpoints
  • P/S of 26.70 is excessive
  • P/B of 8.52 indicates high premium over book
  • PEG of 10.64 suggests overvaluation relative to growth
Future
45/100

Growth is present in top-line revenue but not translating to bottom-line stability.

Positives
  • 130.4% Revenue growth
  • Strong analyst price targets
Watchpoints
  • Year-over-year EPS growth of -550%
  • Consistent earnings misses
Past
20/100

Historical performance is characterized by volatility and consistent losses.

Positives
  • Recent 1-year price recovery
Watchpoints
  • 5-year change is negative (-41.4%)
  • Long history of quarterly losses
Health
15/100

High cash reserves are the only factor preventing immediate insolvency.

Positives
  • Low Debt/Equity
  • High Current Ratio
Watchpoints
  • Piotroski F-Score 1/9
  • Negative ROE (-105.3%)
  • Negative Gross Margin
Dividend
0/100

Typical for early-stage biotech; not a priority.

Positives
No standout positives identified.
Watchpoints
  • No dividend paid
  • No history of payouts

Stock Price & Analyst Targets

Real-time price movements and analyst price targets

Current Price
$1.56
Analyst Target
$4.5
Upside/Downside
+188.5%

Multi-Horizon Performance vs Peers

Price momentum across 5Y → 1W horizons for LCTX and closest competitors.

Updated 2026-04-28
LCT
Lineage Cell Therapeutics, Inc.
Primary
5Y
-41.4%
3Y
+14.7%
1Y
+239.1%
6M
-9.8%
1M
+6.1%
1W
-4.9%
XFO
X4 Pharmaceuticals, Inc.
Peer
5Y
-98.4%
3Y
-90.0%
1Y
-29.0%
6M
+38.5%
1M
+12.0%
1W
+3.4%
NRC
NRC Health
Peer
5Y
-61.4%
3Y
-56.9%
1Y
+63.3%
6M
+52.5%
1M
-0.1%
1W
-5.9%
AKB
Akebia Therapeutics, Inc.
Peer
5Y
-59.4%
3Y
+113.8%
1Y
-13.6%
6M
-50.5%
1M
-5.8%
1W
+15.0%
CYH
Community Health Systems, Inc.
Peer
5Y
-74.0%
3Y
-54.0%
1Y
-5.6%
6M
-33.7%
1M
-7.5%
1W
-13.9%

Positive values indicate cumulative gains over the specified period. Comparables pulled from the same sector to highlight whether momentum is stock-specific or industry-wide.

Historical Performance Trends

Long-term financial metrics and growth patterns

Revenue & Net Income

Profit & Operating Margins

Return on Equity (ROE)

Quarterly Revenue Growth

Historical data shows last 12 quarters (3 years)

Valuation Metrics

Key valuation ratios and pricing indicators

P/E Ratio
N/A
Forward P/E
-20.13
PEG Ratio
10.64
P/B Ratio
8.52
P/S Ratio
26.7
EV/Revenue
22.95
EV/EBITDA
-15.85
Market Cap
$388.58M

Profitability

Profit margins and return metrics

Profit Margin N/A
Operating Margin -99.09%
Gross Margin -22.8%
ROE -105.3%
ROA -12.06%

Growth

Revenue and earnings growth rates

Revenue Growth +130.4%
Earnings Growth N/A
Q/Q Revenue Growth +130.4%
Q/Q Earnings Growth N/A

Financial Health

Balance sheet strength and liquidity metrics

Debt/Equity
0.06
Low debt
Current Ratio
5.2
Strong
Quick Ratio
5.04
Excellent
Cash/Share
$0.22

Financial Statement Flow

Interactive flow visualization showing how money moves through the company Q4 2025

Revenue
$0.0B
Gross Margin
99.0%
Op. Margin
-99.1%
Net Margin
12.9%
Total Assets
$0.1B
Liabilities
$0.1B
Equity
$0.0B
Debt/Equity
1.55x
Operating CF
$-0.0B
CapEx
$-0.0B
Free Cash Flow
$-0.0B
FCF Yield
108%

Quarterly Earnings History

EPS performance vs analyst estimates

2026-05-12
$N/A
2026-03-05
$N/A
+100.0% surprise
2025-11-06
$-0.13
-358.9% surprise
2025-08-12
$-0.13
-355.0% surprise

Healthcare Sector Comparison

Comparing LCTX against 566 companies in the Healthcare sector (36 bullish, 169 neutral, 361 bearish)
Return on Equity (ROE)
-105.3%
This Stock
vs
-87.13%
Sector Avg
+20.8% (Excellent)
Debt to Equity
0.06
This Stock
vs
2.64
Sector Avg
-97.9% (Less Debt)
Revenue Growth
130.4%
This Stock
vs
122.93%
Sector Avg
+6.1% (Growing)
Current Ratio
5.2
This Stock
vs
4.46
Sector Avg
+16.7% (Stronger)

Similar Companies

Peer comparison within the same industry

Recent Insider Trading

Insider buy and sell transactions from the last 6 months

CULLEY BRIAN M
Chief Executive Officer
Buy
2026-03-12
15,000 shares · $24,375
CULLEY BRIAN M
Chief Executive Officer
Stock Award
2026-02-11
31,250 shares
SAMUEL GEORGE A. III
General Counsel
Stock Award
2026-02-11
6,075 shares
CULLEY BRIAN M
Chief Executive Officer
Stock Award
2025-12-19
8,925 shares
SAMUEL GEORGE A. III
General Counsel
Stock Award
2025-12-19
1,735 shares
Insider transactions can signal confidence or concerns about company prospects

SEC Filings

Recent regulatory filings from the SEC EDGAR database

8-K
8-K
2026-03-11
10-K
10-K
2026-03-05

LCTX filed its 10-K on March 5, 2026, which includes standard sections for risk factors, management's discussion and analysis, and financial statements. The provided excerpts consist only of the filing's table of contents and do not contain specific financial highlights or detailed risk disclosures.

8-K
8-K
2026-03-05

LCTX filed an 8-K on March 5, 2026, likely to announce its fourth-quarter and full-year financial results.

8-K
8-K
2025-11-28
8-K
8-K
2025-11-24

Lexeo Therapeutics filed a Form 8-K on November 24, 2025, to disclose a material corporate event.

8-K
8-K
2025-11-12
10-Q
10-Q
2025-11-06

For the nine months ended September 30, 2025, LCTX reported a 20% increase in total revenues to $7.9 million, driven primarily by a 30% rise in collaboration revenues. The company expanded its preclinical pipeline through a new research collaboration with WDI, which provides up to $12 million over three years to advance the development of ReSonance (ANP1). Financial risks include a significant quarterly decline in royalty and license revenues, which fell 65% compared to the prior year.

8-K
8-K
2025-11-06

LCTX filed an 8-K on November 6, 2025, likely to announce its third-quarter financial results.

8-K
8-K
2025-08-26
10-Q
10-Q
2025-08-12

LCTX reported total revenues of $4.267 million for the six months ended June 30, 2025, a 50% increase over the prior year driven primarily by a 66% rise in collaboration revenues. The company is advancing a pipeline of allogeneic cell therapies, including OpRegen in Phase 2a and OPC1 in Phase 1b clinical trials. Financial stability remains dependent on collaboration agreements and the inherent risks associated with clinical-stage development of its neurology and ophthalmic programs.

8-K
8-K
2025-08-12
8-K
8-K
2025-07-02
8-K
8-K
2025-06-23
8-K
8-K
2025-06-09
10-Q
10-Q
2025-05-13
Data sourced from SEC EDGAR. AI summaries generated automatically.

Wall Street Analysts

Professional analyst ratings and price targets

Consensus
STRONG_BUY
6 analysts
Canaccord Genuity
2026-04-28
init
Buy
B. Riley Securities
2026-03-25
Maintains
Buy Buy
HC Wainwright & Co.
2026-03-24
reit
Buy Buy
D. Boral Capital
2026-03-06
Maintains
Buy Buy
D. Boral Capital
2026-02-09
Maintains
Buy Buy
D. Boral Capital
2025-11-25
Maintains
Buy Buy
HC Wainwright & Co.
2025-11-24
Maintains
Buy Buy

Past News Coverage

Recent headlines mentioning LCTX from our newsroom.

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