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ACLX Arcellx, Inc. - Fundamental Analysis

BEARISH
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ACLX Stock | Fundamental Analysis & Investment Insights
NASDAQ Healthcare Biotechnology
Current Price Live
$64.11
Analyst Target
$110.53
+72.4% Upside
52W High
$94.07
52W Low
$47.86

At a glance

Key valuation, profitability, growth, and risk metrics.

Updated Feb 21, 2026
Market cap
$3.71B
P/E
N/A
ROE
-47.2%
Profit margin
N/A
Debt/Equity
0.12
Dividend yield
N/A

AI Analysis

Powered by advanced machine learning algorithms

Confidence Score
85%
Analysis Accuracy
ACLX exhibits severe financial distress despite a strong analyst consensus, as reflected in its Piotroski F-Score of 1/9—indicating weak operational and financial health. The company reports negative profitability across all key margins, with a staggering -1248.25% operating margin and -47.18% ROE, while revenue has collapsed by 81% YoY. Although the debt/equity ratio is low (0.12) and liquidity is high (current ratio 3.99), these are insufficient to offset deteriorating fundamentals. Insider selling totaling $7.12M in six months and a bearish technical trend further undermine confidence. The stock trades at a premium valuation (Price/Sales 103.27) despite negative earnings and no intrinsic value, suggesting overvaluation driven by speculative growth expectations.

Key Strengths

Strong analyst consensus with 'strong_buy' recommendation from 17 analysts
High liquidity with current and quick ratios above 3.9, indicating robust short-term solvency
Low debt/equity ratio (0.12) suggesting minimal leverage risk
Historical periods of significant earnings surprise (e.g., +184% in Q1 2024)
Significant 5-year price appreciation (+281.6%), indicating strong investor interest

Key Risks

Piotroski F-Score of 1/9 signals extreme financial weakness and poor operational efficiency
Negative and deteriorating revenue growth (-81% YoY) and earnings (YoY EPS down -106.2%)
Massive insider selling (13 transactions, $7.12M) with no buys in last 6 months
No profitability: all margins are negative, including ROE (-47.18%) and ROA (-21.34%)
Valuation is extremely stretched (Price/Sales 103.27) with no Graham Number or intrinsic value available

Performance Snowflake

Multi-dimensional analysis across 5 key categories

Overall
21
Weak
Value
20
Future
30
Past
40
Health
15
Dividend
0
AI Verdict
Weak
Key drivers: Extremely low Piotroski F-Score (1/9), Negative and declining revenue and earnings, High insider selling activity, No profitability or cash flow generation, Premium valuation without earnings support
Confidence
85%
Value
20/100

Ref P/E, PEG, Graham Number

Positives
  • Low debt/equity ratio (0.12) reduces financial risk
  • High current and quick ratios (3.99, 3.93) indicate strong liquidity
Watchpoints
  • No Graham Number or intrinsic value available
  • Price/Sales of 103.27 is extremely high for a non-profitable firm
  • Forward P/E of -18.45 reflects deep losses, not value
Future
30/100

Ref Growth rates

Positives
  • Analyst target price of $110.53 implies significant upside from current $64.11
  • Historical volatility in earnings surprises suggests potential for recovery
Watchpoints
  • Revenue down 81% YoY, indicating business contraction
  • Earnings growth is deeply negative (-106.2% YoY)
  • No clear path to profitability or sustainable growth
Past
40/100

Ref Historical trends

Positives
  • Significant past earnings surprises (e.g., +184% in Q1 2024)
  • 5-year price return of +281.6% shows strong historical performance
Watchpoints
  • Consistent earnings misses in recent quarters (e.g., -53.0%, -83.4%, -96.2%)
  • Most recent Q/Q EPS growth is -5.3%
  • Historical losses are extreme (e.g., -557.6% surprise in Q1 2022)
Health
15/100

Ref Altman Z-Score, Piotroski F-Score

Positives
  • Low debt/equity (0.12) and high liquidity (current ratio 3.99)
  • No Altman Z-Score available, but low leverage reduces immediate distress risk
Watchpoints
  • Piotroski F-Score of 1/9 is critically low, indicating severe financial distress
  • Negative ROE, ROA, and operating margin suggest poor capital efficiency
  • No free cash flow or operating cash flow data available
Dividend
0/100

Ref Yield, Payout

Positives
No standout positives identified.
Watchpoints
  • No dividend yield or payout ratio
  • Dividend strength is 0/100, indicating no dividend policy

Stock Price & Analyst Targets

Real-time price movements and analyst price targets

Current Price
$64.11
Analyst Target
$110.53
Upside/Downside
+72.4%

Multi-Horizon Performance vs Peers

Price momentum across 5Y → 1W horizons for ACLX and closest competitors.

Updated 2026-02-20
Company 5Y 3Y 1Y 6M 1M 1W
ACLX
Arcellx, Inc.
Primary
+281.6% +132.1% -2.3% -10.1% -6.9% -6.4%
ADMA
ADMA Biologics, Inc.
Peer
+528.9% +356.1% +0.1% -9.6% -7.3% +0.1%
BLLN
BillionToOne, Inc.
Peer
-19.6% -19.6% -19.6% -19.6% +1.4% -1.3%
ACAD
ACADIA Pharmaceuticals Inc.
Peer
-52.2% +28.8% +18.2% -6.8% -10.3% +8.9%
ARQT
Arcutis Biotherapeutics, Inc.
Peer
-3.6% +63.3% +92.7% +76.3% -11.0% +1.4%

Positive values indicate cumulative gains over the specified period. Comparables pulled from the same sector to highlight whether momentum is stock-specific or industry-wide.

Historical Performance Trends

Long-term financial metrics and growth patterns

Revenue & Net Income

Profit & Operating Margins

Return on Equity (ROE)

Quarterly Revenue Growth

Historical data shows last 12 quarters (3 years)

Valuation Metrics

Key valuation ratios and pricing indicators

P/E Ratio
N/A
Forward P/E
-18.45
PEG Ratio
N/A
P/B Ratio
8.4
P/S Ratio
103.27
EV/Revenue
95.75
EV/EBITDA
-14.58
Market Cap
$3.71B

Profitability

Profit margins and return metrics

Profit Margin N/A
Operating Margin -1248.25%
Gross Margin N/A
ROE -47.18%
ROA -21.34%

Growth

Revenue and earnings growth rates

Revenue Growth -81.0%
Earnings Growth N/A
Q/Q Revenue Growth N/A
Q/Q Earnings Growth N/A

Financial Health

Balance sheet strength and liquidity metrics

Debt/Equity
0.12
Low debt
Current Ratio
3.99
Strong
Quick Ratio
3.93
Excellent
Cash/Share
$7.98

Quarterly Earnings History

EPS performance vs analyst estimates

2026-02-26
$N/A
2025-11-05
$-0.99
+4.1% surprise
2025-08-07
$-0.94
+8.9% surprise
2025-05-08
$-1.13
-53.0% surprise

Healthcare Sector Comparison

Comparing ACLX against 146 companies in the Healthcare sector (11 bullish, 60 neutral, 75 bearish)
Return on Equity (ROE)
-47.18%
This Stock
vs
-56.86%
Sector Avg
-17.0% (Below Avg)
Debt to Equity
0.12
This Stock
vs
2.68
Sector Avg
-95.6% (Less Debt)
Revenue Growth
-81.0%
This Stock
vs
62.23%
Sector Avg
-230.2% (Slower)
Current Ratio
3.99
This Stock
vs
3.45
Sector Avg
+15.6% (Stronger)

Similar Companies

Peer comparison within the same industry

Company AI Rating Market Cap P/E ROE Profit Margin Price
ACLX
Arcellx, Inc.
BEARISH $3.71B - -47.2% -% $64.11
ADMA
ADMA Biologics, Inc.
NEUTRAL $3.84B 18.72 63.2% 42.9% $16.1
BLLN
BillionToOne, Inc.
NEUTRAL $4.01B - -% -4.4% $87.57
ACAD
ACADIA Pharmaceuticals Inc.
BULLISH $4.06B 15.48 35.0% 24.9% $23.99
ARQT
Arcutis Biotherapeutics, Inc.
NEUTRAL $3.21B - -28.2% -13.9% $26.2

Recent Insider Trading

Insider buy and sell transactions from the last 6 months

Date Insider Position Transaction Shares Value
2026-02-19 GILSON MICHELLE Chief Financial Officer Sale 8,384 $572,568
2026-02-17 GILSON MICHELLE Chief Financial Officer Sale 11,291 $784,783
2026-02-11 ELGHANDOUR RAMI Chief Executive Officer Gift 218,500 -
2026-02-11 ELGHANDOUR RAMI Chief Executive Officer Gift 198,000 -
2026-01-20 LUBNER DAVID CHARLES Director Sale 6,000 $450,000
2026-01-20 LUBNER DAVID CHARLES Director Option Exercise 6,000 $37,680
2026-01-14 HEERY CHRISTOPHER RYAN Officer Sale 5,882 $402,997
2026-01-13 HEERY CHRISTOPHER RYAN Officer Sale 7,437 $487,213
2026-01-12 HEERY CHRISTOPHER RYAN Officer Sale 6,131 $393,286
2026-01-06 HEERY CHRISTOPHER RYAN Officer Stock Award 42,605 -
2026-01-06 GILSON MICHELLE Chief Financial Officer Stock Award 56,366 -
2026-01-06 ELGHANDOUR RAMI Officer and Director Stock Award 164,548 -
2025-11-17 HEERY CHRISTOPHER RYAN Officer Sale 340 $30,600
2025-10-15 GILSON MICHELLE Chief Financial Officer Sale 5,364 $488,315
2025-10-06 GILSON MICHELLE Chief Financial Officer Sale 5,946 $511,603
Insider transactions can signal confidence or concerns about company prospects

Wall Street Analysts

Professional analyst ratings and price targets

Consensus
STRONG_BUY
17 analysts
Needham
2026-02-05
reit
Buy Buy
HC Wainwright & Co.
2026-02-04
reit
Buy Buy
Wells Fargo
2025-12-22
init
Overweight
Canaccord Genuity
2025-12-08
Maintains
Buy Buy
Needham
2025-12-08
reit
Buy Buy
Wolfe Research
2025-11-18
init
Peer Perform
Canaccord Genuity
2025-11-03
Maintains
Buy Buy

Past News Coverage

Recent headlines mentioning ACLX from our newsroom.

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