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GYRE

BEARISH
$7.39 Live
Gyre Therapeutics, Inc. · NASDAQ
Target $18.67 (+152.6%)
$6.57 52W Range $11.78

At a glance

Key valuation, profitability, growth, and risk metrics.

Updated Apr 11, 2026
Market cap
$711.9M
P/E
369.5
ROE
8.2%
Profit margin
4.3%
Debt/Equity
0.01
Dividend yield
N/A

AI Analysis

AI-powered fundamental assessment

Confidence
85%
GYRE exhibits significant financial fragility and valuation misalignment, evidenced by a weak Piotroski F-Score of 3/9 and a Graham Number of $0.72, which is a fraction of the current $7.39 price. While the company maintains a strong liquidity position with a Current Ratio of 5.60 and negligible debt, its valuation is extreme with a P/E ratio of 369.50. The disconnect between the intrinsic value ($0.14) and the market price suggests the stock is trading on speculative future expectations rather than current fundamentals. Technical trends are entirely bearish (0/100), and earnings consistency is poor, with only one beat in the last four quarters.

Key Strengths

Exceptionally low Debt/Equity ratio (0.01)
Strong short-term liquidity (Current Ratio 5.60)
High Gross Margin (95.36%) indicating strong product pricing power
Consistent revenue growth (33.4% YoY)
Significant upside gap to analyst target price ($18.67)

Key Risks

Extreme valuation premium (P/E 369.50 vs Sector Avg 43.24)
Weak operational health as indicated by Piotroski F-Score (3/9)
Severe divergence between current price and Graham/Intrinsic value
Poor earnings track record with a recent Q/Q EPS collapse of -166.7%
Bearish technical momentum and negative 1-month price action
AI Fair Value Estimate
Based on comprehensive analysis
$1.25
-83.1% below current price

Performance Snowflake

Multi-dimensional analysis across 5 key categories

Overall
27
Weak
Value
10
Future
55
Past
30
Health
40
Dividend
0
AI Verdict
Speculative Overvaluation
Key drivers: Extreme P/E ratio, Low Piotroski F-Score, Strong balance sheet liquidity, Bearish technicals
Confidence
90%
Value
10/100

Ref P/E, PEG, Graham Number

Positives
No standout positives identified.
Watchpoints
  • P/E of 369.50
  • Price/Book of 6.37
  • Current price is >10x the Graham Number
Future
55/100

Ref Growth rates

Positives
  • 33.4% Revenue Growth
  • High Analyst Target Price
Watchpoints
  • Volatile EPS
  • Poor earnings surprise history
Past
30/100

Ref Historical trends

Positives
  • 3Y Change +134.6%
Watchpoints
  • 5Y Change -40%
  • Recent 1M decline of 11.3%
Health
40/100

Ref Altman Z-Score, Piotroski F-Score

Positives
  • Debt/Equity 0.01
  • Current Ratio 5.60
Watchpoints
  • Piotroski F-Score 3/9
Dividend
0/100

Ref Yield, Payout

Positives
No standout positives identified.
Watchpoints
  • No dividend paid

Stock Price & Analyst Targets

Real-time price movements and analyst price targets

Current Price
$7.39
Analyst Target
$18.67
Upside/Downside
+152.6%

Multi-Horizon Performance vs Peers

Price momentum across 5Y → 1W horizons for GYRE and closest competitors.

Updated 2026-04-10
GYR
Gyre Therapeutics, Inc.
Primary
5Y
-40.0%
3Y
+134.6%
1Y
+1.4%
6M
-7.2%
1M
-11.3%
1W
+3.8%
ETO
Eton Pharmaceuticals, Inc.
Peer
5Y
+251.9%
3Y
+598.3%
1Y
+130.1%
6M
+26.1%
1M
+58.0%
1W
+4.1%
BBN
Beta Bionics, Inc.
Peer
5Y
-32.5%
3Y
-32.5%
1Y
-32.5%
6M
+7.5%
1M
-48.7%
1W
-13.7%
GDR
GoodRx Holdings, Inc.
Peer
5Y
-94.7%
3Y
-62.4%
1Y
-53.9%
6M
-53.5%
1M
-10.0%
1W
+5.4%
BGM
BGM Group Ltd.
Peer
5Y
-90.8%
3Y
-38.2%
1Y
-66.0%
6M
-64.4%
1M
-12.5%
1W
0.0%

Positive values indicate cumulative gains over the specified period. Comparables pulled from the same sector to highlight whether momentum is stock-specific or industry-wide.

Historical Performance Trends

Long-term financial metrics and growth patterns

Revenue & Net Income

Profit & Operating Margins

Return on Equity (ROE)

Quarterly Revenue Growth

Historical data shows last 12 quarters (3 years)

Valuation Metrics

Key valuation ratios and pricing indicators

P/E Ratio
369.5
Forward P/E
123.17
PEG Ratio
N/A
P/B Ratio
6.37
P/S Ratio
6.11
EV/Revenue
5.66
EV/EBITDA
47.08
Market Cap
$711.9M

Profitability

Profit margins and return metrics

Profit Margin 4.31%
Operating Margin 0.32%
Gross Margin 95.36%
ROE 8.21%
ROA 4.93%

Growth

Revenue and earnings growth rates

Revenue Growth +33.4%
Earnings Growth N/A
Q/Q Revenue Growth +33.45%
Q/Q Earnings Growth N/A

Financial Health

Balance sheet strength and liquidity metrics

Debt/Equity
0.01
Low debt
Current Ratio
5.6
Strong
Quick Ratio
4.58
Excellent
Cash/Share
$0.57

Financial Statement Flow

Interactive flow visualization showing how money moves through the company Q4 2025

Revenue
$0.0B
Gross Margin
95.3%
Op. Margin
0.3%
Net Margin
-4.6%
Total Assets
$0.2B
Liabilities
$0.0B
Equity
$0.1B
Debt/Equity
0.22x
Operating CF
$-0.0B
CapEx
$-0.0B
Free Cash Flow
$-0.0B
FCF Yield
102%

Quarterly Earnings History

EPS performance vs analyst estimates

2026-05-07
$N/A
2026-03-12
$-0.02
-137.5% surprise
2025-11-07
$0.03
+250.0% surprise
2025-08-11
$N/A
-100.0% surprise

Healthcare Sector Comparison

Comparing GYRE against 226 companies in the Healthcare sector (19 bullish, 76 neutral, 131 bearish)
P/E Ratio
369.5
This Stock
vs
45.29
Sector Avg
+715.9% (Expensive)
Return on Equity (ROE)
8.21%
This Stock
vs
-40.43%
Sector Avg
-120.3% (Below Avg)
Profit Margin
4.31%
This Stock
vs
-18.65%
Sector Avg
-123.1% (Weaker)
Debt to Equity
0.01
This Stock
vs
4.61
Sector Avg
-99.9% (Less Debt)
Revenue Growth
33.4%
This Stock
vs
97.21%
Sector Avg
-65.6% (Slower)
Current Ratio
5.6
This Stock
vs
3.51
Sector Avg
+59.5% (Stronger)

Similar Companies

Peer comparison within the same industry

Past News Coverage

Recent headlines mentioning GYRE from our newsroom.

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