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OBIO

NEUTRAL
$4.57 Live
Orchestra BioMed Holdings, Inc. · NASDAQ
Target $12.43 (+172.0%)
$2.2 52W Range $5.42

At a glance

Key valuation, profitability, growth, and risk metrics.

Updated Apr 16, 2026
Market cap
$267.44M
P/E
N/A
ROE
-109.4%
Profit margin
-157.4%
Debt/Equity
0.25
Dividend yield
N/A

AI Analysis

AI-powered fundamental assessment

Confidence
85%
OBIO presents a high-risk, high-reward speculative profile, anchored by a critically weak Piotroski F-Score of 1/9 which indicates severe fundamental instability. Despite this, the company maintains a strong liquidity position with a current ratio of 6.45 and low debt-to-equity (0.25), providing a necessary runway for its biotech operations. Explosive revenue growth (12,120%) and a strong analyst consensus target of $12.43 suggest significant upside potential, yet these are countered by a 0/100 technical trend and deep negative profit margins. The stock is currently a battle between deteriorating deterministic health scores and optimistic future growth projections.

Key Strengths

Exceptional short-term liquidity (Current Ratio: 6.45)
Astronomical year-over-year revenue growth (12,120%)
Strong analyst consensus with a 'strong_buy' rating and $12.43 target
Low leverage with a Debt/Equity ratio of 0.25
High gross margins (99.43%) typical of high-value biotech IP

Key Risks

Critically low Piotroski F-Score (1/9) signaling poor financial health
Severe negative profit margins (-157.40%) indicating high cash burn
Bearish technical trend (0/100) despite recent price gains
High valuation multiples (P/S: 7.99, P/B: 4.87) relative to current earnings
Binary risk associated with biotechnology clinical outcomes
AI Fair Value Estimate
Based on comprehensive analysis
$12.43
+172.0% above current price

Performance Snowflake

Multi-dimensional analysis across 5 key categories

Overall
30
Weak
Value
30
Future
85
Past
20
Health
15
Dividend
0
AI Verdict
Speculative Growth
Key drivers: Extreme revenue growth, Strong analyst targets, Poor deterministic health scores, High liquidity runway
Confidence
80%
Value
30/100

Trades at a significant premium to book value; valuation is based on future pipeline rather than current fundamentals.

Positives
  • Significant upside to analyst target price
Watchpoints
  • High Price/Book (4.87)
  • High Price/Sales (7.99)
  • No Graham Number available due to lack of earnings
Future
85/100

Growth metrics are extreme, suggesting a transition from R&D to commercialization or milestone payments.

Positives
  • 12,120% YoY revenue growth
  • Recent EPS surprise of +168.7%
  • Strong buy recommendation from 7 analysts
Watchpoints
  • Sustainability of growth from a near-zero base
Past
20/100

Long-term historical performance has been poor, though short-term momentum is improving.

Positives
  • 1-year price recovery of +62.1%
Watchpoints
  • 3-year change of -79.2%
  • 5-year change of -56.0%
Health
15/100

Deterministic health is very weak (F-Score), though the balance sheet provides a temporary liquidity cushion.

Positives
  • Low Debt/Equity (0.25)
  • High Current Ratio (6.45)
Watchpoints
  • Piotroski F-Score of 1/9
  • Negative ROE (-109.41%)
  • Negative ROA (-33.90%)
Dividend
0/100

Non-dividend paying growth company.

Positives
No standout positives identified.
Watchpoints
  • No dividend paid
  • 0/100 dividend strength

Stock Price & Analyst Targets

Real-time price movements and analyst price targets

Current Price
$4.57
Analyst Target
$12.43
Upside/Downside
+172.0%

Multi-Horizon Performance vs Peers

Price momentum across 5Y → 1W horizons for OBIO and closest competitors.

Updated 2026-04-15
OBI
Orchestra BioMed Holdings, Inc.
Primary
5Y
-56.0%
3Y
-79.2%
1Y
+62.1%
6M
+24.9%
1M
+0.4%
1W
+7.0%
EOL
Evolus, Inc.
Peer
5Y
-69.9%
3Y
-50.5%
1Y
-56.3%
6M
-34.1%
1M
-23.6%
1W
-5.1%
MAS
908 Devices Inc.
Peer
5Y
-85.9%
3Y
-13.6%
1Y
+62.9%
6M
-8.5%
1M
+18.6%
1W
+5.1%
CLP
ClearPoint Neuro, Inc.
Peer
5Y
-59.8%
3Y
-1.5%
1Y
-17.2%
6M
-65.6%
1M
-21.4%
1W
-0.3%
CAR
Carlsmed, Inc.
Peer
5Y
-32.8%
3Y
-32.8%
1Y
-32.8%
6M
-28.3%
1M
-18.4%
1W
+7.6%

Positive values indicate cumulative gains over the specified period. Comparables pulled from the same sector to highlight whether momentum is stock-specific or industry-wide.

Historical Performance Trends

Long-term financial metrics and growth patterns

Revenue & Net Income

Profit & Operating Margins

Return on Equity (ROE)

Quarterly Revenue Growth

Historical data shows last 12 quarters (3 years)

Valuation Metrics

Key valuation ratios and pricing indicators

P/E Ratio
N/A
Forward P/E
-2.68
PEG Ratio
N/A
P/B Ratio
4.87
P/S Ratio
7.99
EV/Revenue
5.58
EV/EBITDA
-3.63
Market Cap
$267.44M

Profitability

Profit margins and return metrics

Profit Margin -157.4%
Operating Margin 21.85%
Gross Margin 99.43%
ROE -109.41%
ROA -33.9%

Growth

Revenue and earnings growth rates

Revenue Growth +12120.2%
Earnings Growth N/A
Q/Q Revenue Growth +12120.2%
Q/Q Earnings Growth N/A

Financial Health

Balance sheet strength and liquidity metrics

Debt/Equity
0.25
Low debt
Current Ratio
6.45
Strong
Quick Ratio
6.37
Excellent
Cash/Share
$1.82

Financial Statement Flow

Interactive flow visualization showing how money moves through the company Q4 2025

Revenue
$0.0B
Gross Margin
99.8%
Op. Margin
21.8%
Net Margin
20.2%
Total Assets
$0.1B
Liabilities
$0.1B
Equity
$0.1B
Debt/Equity
1.14x
Operating CF
$-0.0B
CapEx
$-0.0B
Free Cash Flow
$-0.0B
FCF Yield
101%

Quarterly Earnings History

EPS performance vs analyst estimates

2026-05-08
$N/A
2026-03-12
$0.26
+168.7% surprise
2025-11-10
$-0.4
+6.7% surprise
2025-08-12
$-0.5
+1.4% surprise

Healthcare Sector Comparison

Comparing OBIO against 421 companies in the Healthcare sector (25 bullish, 134 neutral, 262 bearish)
Return on Equity (ROE)
-109.41%
This Stock
vs
-100.15%
Sector Avg
+9.2% (Above Avg)
Profit Margin
-157.4%
This Stock
vs
-13.63%
Sector Avg
+1054.9% (Superior)
Debt to Equity
0.25
This Stock
vs
3.22
Sector Avg
-92.2% (Less Debt)
Revenue Growth
12120.2%
This Stock
vs
121.05%
Sector Avg
+9912.2% (Fast Growth)
Current Ratio
6.45
This Stock
vs
4.55
Sector Avg
+41.7% (Stronger)

Similar Companies

Peer comparison within the same industry

Recent Insider Trading

Insider buy and sell transactions from the last 6 months

HOCHMAN DAVID P
Chief Executive Officer
Buy
2026-03-13
10,000 shares · $42,900
SHERMAN DARREN
President
Stock Award
2026-02-12
397,000 shares
TAYLOR ANDREW LAWRENCE
Chief Financial Officer
Stock Award
2026-02-12
181,000 shares
HOCHMAN DAVID P
Chief Executive Officer
Stock Award
2026-02-12
504,000 shares
HOCHMAN DAVID P
Chief Executive Officer
Buy
2025-11-14
5,000 shares · $20,350
Insider transactions can signal confidence or concerns about company prospects

Wall Street Analysts

Professional analyst ratings and price targets

Consensus
STRONG_BUY
7 analysts
Chardan Capital
2026-03-12
Maintains
Buy Buy
Barclays
2026-01-09
Maintains
Overweight Overweight
TD Cowen
2025-12-10
init
Buy
Chardan Capital
2025-11-13
Maintains
Buy Buy
Barclays
2025-11-12
Maintains
Overweight Overweight

Past News Coverage

Recent headlines mentioning OBIO from our newsroom.

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