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TLSA

BEARISH
$1.21 Live
Tiziana Life Sciences Ltd · NASDAQ
Target $8.02 (+562.6%)
$1.05 52W Range $2.6

At a glance

Key valuation, profitability, growth, and risk metrics.

Updated Apr 21, 2026
Market cap
$153.97M
P/E
N/A
ROE
-232.3%
Profit margin
N/A
Debt/Equity
0.01
Dividend yield
N/A

AI Analysis

AI-powered fundamental assessment

Confidence
85%
TLSA exhibits significant financial fragility, highlighted by a weak Piotroski F-Score of 3/9 and a complete lack of revenue generation. The company is operating with extreme negative returns on equity (-232.31%) and assets (-83.78%), indicating a high cash-burn rate typical of early-stage biotechnology firms. While the balance sheet shows low leverage (Debt/Equity 0.01) and adequate short-term liquidity (Current Ratio 1.72), the valuation is disconnected from fundamentals with a Price-to-Book ratio of 15.71. The technical trend is purely bearish, and the lack of operational growth makes this a highly speculative asset.

Key Strengths

Very low debt-to-equity ratio (0.01)
Healthy current ratio (1.72) providing short-term liquidity
Strong analyst price target ($8.02) relative to current price
Low absolute debt levels
Positive short-term 1-week price momentum (+5.2%)

Key Risks

Pre-revenue status with no reported revenue growth
Severe negative ROE (-232.31%) indicating massive capital erosion
Extremely high Price-to-Book ratio (15.71) suggesting overvaluation
Bearish technical trend (0/100 score)
High dependency on single-analyst projections for valuation support

Performance Snowflake

Multi-dimensional analysis across 5 key categories

Overall
20
Weak
Value
15
Future
30
Past
20
Health
35
Dividend
0
AI Verdict
High-Risk Speculative
Key drivers: Lack of revenue, Weak Piotroski score, Extreme negative profitability, Bearish technicals
Confidence
90%
Value
15/100

Graham Number and Intrinsic Value are unavailable due to lack of earnings and positive book value utility.

Positives
No standout positives identified.
Watchpoints
  • P/B ratio of 15.71 is excessive for a non-earning entity
  • No P/E or PEG available due to lack of earnings
Future
30/100

Future value is entirely dependent on binary clinical trial outcomes.

Positives
  • High analyst target price suggests potential clinical catalyst
Watchpoints
  • No historical revenue or earnings growth to project from
Past
20/100

Long-term trend is decisively negative.

Positives
  • 1-year return is slightly positive (+7.1%)
Watchpoints
  • 5-year change is -51.0%
  • 6-month change is -38.3%
Health
35/100

Liquidity is currently stable, but operational health is failing.

Positives
  • Low Debt/Equity
  • Current Ratio > 1.5
Watchpoints
  • Piotroski F-Score of 3/9 indicates weak financial health
  • Severe negative ROA
Dividend
0/100

Company is in a growth/burn phase; dividends are not applicable.

Positives
No standout positives identified.
Watchpoints
  • No dividend paid
  • 0/100 dividend strength

Stock Price & Analyst Targets

Real-time price movements and analyst price targets

Current Price
$1.21
Analyst Target
$8.02
Upside/Downside
+562.6%

Multi-Horizon Performance vs Peers

Price momentum across 5Y → 1W horizons for TLSA and closest competitors.

Updated 2026-04-20
TLS
Tiziana Life Sciences Ltd
Primary
5Y
-51.0%
3Y
+16.4%
1Y
+7.1%
6M
-38.3%
1M
0.0%
1W
+5.2%
TKN
Alpha Teknova, Inc.
Peer
5Y
-88.4%
3Y
+41.3%
1Y
-49.6%
6M
-49.4%
1M
+4.3%
1W
-3.6%
RCE
AVITA Medical, Inc.
Peer
5Y
-74.5%
3Y
-65.7%
1Y
-44.2%
6M
+28.8%
1M
+22.7%
1W
+2.6%
APY
Apyx Medical Corporation
Peer
5Y
-68.5%
3Y
+28.3%
1Y
+249.0%
6M
+72.9%
1M
-7.4%
1W
+16.4%
SPR
Spero Therapeutics, Inc.
Peer
5Y
-77.5%
3Y
+57.1%
1Y
+264.7%
6M
+24.4%
1M
+11.8%
1W
+3.0%

Positive values indicate cumulative gains over the specified period. Comparables pulled from the same sector to highlight whether momentum is stock-specific or industry-wide.

Historical Performance Trends

Long-term financial metrics and growth patterns

Revenue & Net Income

Profit & Operating Margins

Return on Equity (ROE)

Quarterly Revenue Growth

Historical data shows last 12 quarters (3 years)

Valuation Metrics

Key valuation ratios and pricing indicators

P/E Ratio
N/A
Forward P/E
-6.06
PEG Ratio
N/A
P/B Ratio
15.71
P/S Ratio
N/A
EV/Revenue
N/A
EV/EBITDA
-7.4
Market Cap
$153.97M

Profitability

Profit margins and return metrics

Profit Margin N/A
Operating Margin N/A
Gross Margin N/A
ROE -232.31%
ROA -83.78%

Growth

Revenue and earnings growth rates

Revenue Growth N/A
Earnings Growth N/A
Q/Q Revenue Growth N/A
Q/Q Earnings Growth N/A

Financial Health

Balance sheet strength and liquidity metrics

Debt/Equity
0.01
Low debt
Current Ratio
1.72
Good
Quick Ratio
1.65
Excellent
Cash/Share
$0.06

Financial Statement Flow

Interactive flow visualization showing how money moves through the company Q4 2024

Total Assets
$0.0B
Liabilities
$0.0B
Equity
$0.0B
Debt/Equity
1.87x

Quarterly Earnings History

EPS performance vs analyst estimates

2022-12-27
$-0.06
2022-05-22
$-0.06
+7.2% surprise

Healthcare Sector Comparison

Comparing TLSA against 498 companies in the Healthcare sector (28 bullish, 153 neutral, 317 bearish)
Return on Equity (ROE)
-232.31%
This Stock
vs
-95.47%
Sector Avg
+143.3% (Excellent)
Debt to Equity
0.01
This Stock
vs
2.89
Sector Avg
-99.6% (Less Debt)
Current Ratio
1.72
This Stock
vs
4.66
Sector Avg
-63.1% (Weaker)

Similar Companies

Peer comparison within the same industry

SEC Filings

Recent regulatory filings from the SEC EDGAR database

20-F
ANNUAL REPORT
2025-05-06

Tesla filed its 20-F annual report on May 6, 2025, providing a comprehensive overview of its yearly financial performance and operational highlights. The filing contains detailed disclosures regarding the company's financial position and the primary risk factors impacting its business operations.

20-F
ANNUAL REPORT
2024-05-10

Tesla filed its Annual Report on Form 20-F on May 10, 2024, providing a comprehensive disclosure of its yearly financial performance. The report details the company's financial highlights and the primary operational and market risks facing the business.

Data sourced from SEC EDGAR. AI summaries generated automatically.

Past News Coverage

Recent headlines mentioning TLSA from our newsroom.

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