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XBIO

BEARISH
$3.13 Live
Xenetic Biosciences, Inc. · NASDAQ
$1.9 52W Range $13.93

At a glance

Key valuation, profitability, growth, and risk metrics.

Updated Apr 24, 2026
Market cap
$7.17M
P/E
N/A
ROE
-40.0%
Profit margin
-90.1%
Debt/Equity
0.0
Dividend yield
N/A

AI Analysis

AI-powered fundamental assessment

Confidence
85%
XBIO exhibits severe financial fragility, highlighted by a Piotroski F-Score of 1/9, indicating critical weakness in fundamental health. While the company maintains a strong liquidity position with a Current Ratio of 8.32 and zero debt, it suffers from extreme operational inefficiency with a profit margin of -90.07%. Despite recent earnings beats and modest revenue growth, the technical trend is completely bearish (0/100) and the long-term price performance is devastating (-84.6% over 5 years). The company remains a high-risk speculative play dependent on future drug candidate success rather than current financial strength.

Key Strengths

Zero debt (Debt/Equity: 0.00)
High short-term liquidity (Current Ratio: 8.32)
Positive revenue growth (YoY: 18.10%)
Recent track record of beating earnings estimates (4/4 last 4 quarters)
Trading near book value (Price/Book: 0.97)

Key Risks

Critical financial health (Piotroski F-Score: 1/9)
Severe lack of profitability (Profit Margin: -90.07%)
Extreme micro-cap volatility (Market Cap: $0.01B)
Strongly bearish technical trend (0/100)
High dependency on regulatory approvals for drug candidates

Performance Snowflake

Multi-dimensional analysis across 5 key categories

Overall
24
Weak
Value
40
Future
45
Past
20
Health
15
Dividend
0
AI Verdict
High-Risk Speculative
Key drivers: Piotroski F-Score of 1/9, Negative 90% profit margins, Bearish technicals, Zero debt/High liquidity
Confidence
90%
Value
40/100

Ref P/E N/A, P/B 0.97

Positives
  • P/B ratio of 0.97 suggests the stock is not overvalued relative to assets
Watchpoints
  • No P/E or Graham Number due to lack of earnings
Future
45/100

Ref Growth rates

Positives
  • Revenue growth of 18.10%
  • Improving EPS trajectory (YoY +67.6%)
Watchpoints
  • Earnings remain deeply negative
Past
20/100

Ref Historical trends

Positives
  • Recent 1Y return of +22.8%
Watchpoints
  • 5Y change of -84.6% indicates long-term value destruction
Health
15/100

Ref Piotroski F-Score

Positives
  • No debt
  • High current ratio
Watchpoints
  • Piotroski F-Score 1/9 indicates failing fundamental health
Dividend
0/100

Ref Yield N/A

Positives
No standout positives identified.
Watchpoints
  • No dividend payments

Stock Price & Analyst Targets

Real-time price movements and analyst price targets

Current Price
$3.13

Multi-Horizon Performance vs Peers

Price momentum across 5Y → 1W horizons for XBIO and closest competitors.

Updated 2026-04-23
XBI
Xenetic Biosciences, Inc.
Primary
5Y
-84.6%
3Y
-28.5%
1Y
+22.8%
6M
-18.9%
1M
+4.7%
1W
-12.1%
LUC
Lucyd, Inc
Peer
5Y
-99.1%
3Y
-98.6%
1Y
-48.1%
6M
-41.2%
1M
-1.8%
1W
+1.9%
ITO
iTonic Holdings Ltd.
Peer
5Y
-92.6%
3Y
-92.6%
1Y
-90.8%
6M
-60.0%
1M
-17.4%
1W
-8.2%
MGR
Mangoceuticals, Inc.
Peer
5Y
-99.3%
3Y
-97.5%
1Y
-78.4%
6M
-84.5%
1M
+2.4%
1W
+2.4%
BMR
Biomerica, Inc.
Peer
5Y
-95.7%
3Y
-88.5%
1Y
-46.5%
6M
-34.3%
1M
-3.0%
1W
0.0%

Positive values indicate cumulative gains over the specified period. Comparables pulled from the same sector to highlight whether momentum is stock-specific or industry-wide.

Historical Performance Trends

Long-term financial metrics and growth patterns

Revenue & Net Income

Profit & Operating Margins

Return on Equity (ROE)

Quarterly Revenue Growth

Historical data shows last 12 quarters (3 years)

Valuation Metrics

Key valuation ratios and pricing indicators

P/E Ratio
N/A
Forward P/E
-4.74
PEG Ratio
N/A
P/B Ratio
0.97
P/S Ratio
2.41
EV/Revenue
-0.24
EV/EBITDA
N/A
Market Cap
$7.17M

Profitability

Profit margins and return metrics

Profit Margin -90.07%
Operating Margin -81.3%
Gross Margin 100.0%
ROE -40.0%
ROA -23.21%

Growth

Revenue and earnings growth rates

Revenue Growth +18.1%
Earnings Growth N/A
Q/Q Revenue Growth +18.11%
Q/Q Earnings Growth N/A

Financial Health

Balance sheet strength and liquidity metrics

Debt/Equity
0.0
Low debt
Current Ratio
8.32
Strong
Quick Ratio
8.14
Excellent
Cash/Share
$3.44

Financial Statement Flow

Interactive flow visualization showing how money moves through the company Q4 2025

Revenue
$0.0B
Op. Margin
-81.3%
Net Margin
-75.6%
Total Assets
$0.0B
Liabilities
$0.0B
Equity
$0.0B
Debt/Equity
0.13x
Operating CF
$-0.0B
Free Cash Flow
$-0.0B
FCF Yield
100%

Quarterly Earnings History

EPS performance vs analyst estimates

2026-03-12
$-0.22
+57.7% surprise
2025-11-12
$-0.33
+32.6% surprise
2025-08-12
$-0.45
+29.7% surprise
2025-05-13
$-0.59
+18.1% surprise

Healthcare Sector Comparison

Comparing XBIO against 528 companies in the Healthcare sector (28 bullish, 156 neutral, 344 bearish)
Return on Equity (ROE)
-40.0%
This Stock
vs
-92.94%
Sector Avg
-57.0% (Below Avg)
Profit Margin
-90.07%
This Stock
vs
-16.56%
Sector Avg
+444.0% (Superior)
Debt to Equity
0.0
This Stock
vs
2.75
Sector Avg
-100.0% (Less Debt)
Revenue Growth
18.1%
This Stock
vs
131.76%
Sector Avg
-86.3% (Slower)
Current Ratio
8.32
This Stock
vs
4.62
Sector Avg
+79.9% (Stronger)

Similar Companies

Peer comparison within the same industry

SEC Filings

Recent regulatory filings from the SEC EDGAR database

8-K
CURRENT REPORT
2026-03-13
10-K
FORM 10-K FOR DEC 2025
2026-03-12

XBIO's 10-K filing for the period ending December 2025 does not provide specific financial highlights in the provided excerpts. However, the company identifies geopolitical instability, specifically conflicts in Ukraine and the Middle East and related sanctions, as significant risks to its future results and financial position.

8-K
FORM 8-K
2026-01-09
8-K
CURRENT REPORT
2025-12-11
8-K
CURRENT REPORT
2025-11-13
10-Q
FORM 10-Q FOR SEP 2025
2025-11-12

As of September 30, 2025, Xenetic Biosciences, Inc. reported a decrease in cash and equivalents to $4.12 million from $6.17 million at year-end 2024, with total assets declining to $5.07 million. Total liabilities increased to $1.11 million, driven primarily by a rise in accounts payable. These trends indicate a tightening liquidity position and increasing short-term obligations.

DEF 14A
DEFINITIVE PROXY STATEMENT
2025-10-31

XBIO filed a Definitive Proxy Statement on October 31, 2025, providing shareholders with information and voting materials for an upcoming meeting.

8-K
CURRENT REPORT
2025-10-14
8-K
FORM 8-K
2025-08-13

Xencor, Inc. (XBIO) filed a Form 8-K on August 13, 2025, likely to announce its second-quarter financial results or a material update regarding its clinical pipeline.

10-Q
FORM 10-Q FOR JUN 2025
2025-08-12

Xenetic Biosciences, Inc. reported a decrease in cash and equivalents to $4.78 million as of June 30, 2025, down from $6.17 million at year-end 2024. Total assets declined to $5.35 million, while total liabilities remained relatively stable at $903,430. The primary financial risk is the reduction in liquidity and the associated cash burn required to sustain operations.

8-K
FORM 8-K
2025-05-14
10-Q
FORM 10-Q FOR MAR 2025
2025-05-13
8-K
FORM 8-K
2025-04-10
8-K
CURRENT REPORT
2025-03-19
8-K/A
AMENDMENT NO 1
2025-03-19
Data sourced from SEC EDGAR. AI summaries generated automatically.

Past News Coverage

Recent headlines mentioning XBIO from our newsroom.

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