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Corporate Score 45 Bullish

Viking Therapeutics Positions as High-Upside Challenger in Obesity Drug Market

Apr 26, 2026 14:22 UTC
VKTX, NVO, LLY
Medium term

Wall Street analysts project significant growth for Viking Therapeutics as its dual-agonist weight-loss candidate shows promising efficacy and tolerability. The company aims to disrupt the current dominance of Novo Nordisk and Eli Lilly.

  • Consensus price target for VKTX set at $93.59
  • VK2735 injectable achieved 14.7% weight loss in 13 weeks
  • Drug targets both GLP-1 and GIP receptors for enhanced efficacy
  • Better tolerability profile compared to NVO and LLY products
  • Oral version Phase 3 trials expected to start next quarter
  • Phase 2 oral trials saw a high dropout rate of roughly 33%

Viking Therapeutics (VKTX) is emerging as a high-potential contender in the competitive obesity drug market, with Wall Street analysts projecting a consensus one-year price target of $93.59. This target represents a potential increase of over 170% from current trading levels, reflecting optimism surrounding the company's clinical pipeline. The weight-loss landscape is currently dominated by Novo Nordisk’s Wegovy and Eli Lilly’s Zepbound. While these GLP-1 based treatments have established a strong foothold, the market remains open to alternatives that can offer better patient outcomes or fewer side effects, providing an entry point for developers like Viking. Viking's lead candidate, VK2735, is a dual agonist targeting both GLP-1 and GIP receptors. In clinical trials for its weekly injectable form, the drug achieved an average weight loss of 14.7% within just 13 weeks, outperforming several existing options in the category. A primary differentiator for VK2735 is its tolerability profile. While users of current market leaders frequently report nausea and other gastrointestinal issues, Viking's injectable has demonstrated higher patient adherence and better tolerability during trials. The company is also advancing an oral version of the drug, which is currently in Phase 2 testing with Phase 3 trials expected to commence next quarter. However, the oral formulation has faced hurdles, with approximately one-third of participants discontinuing usage during Phase 2 testing due to adverse effects.

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