The Coinbase Premium has flipped negative, signaling a decline in U.S.-based institutional buying pressure. On-chain data reveals nearly $6 billion in realized losses as investors exit positions established at higher price levels.
- Coinbase Premium turned negative after peaking on April 22
- Realized losses hit $5.97 billion as BTC traded near $78,000
- Institutional buyers from late 2025/early 2026 are using bounces to exit
- Realized losses dropped to $4.7 billion by April 28
- Pantera Capital views BTC as 43% below historical trend
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