Nasdaq 100 Sees Divergent Price Action Led by Datadog and Amgen

May 01, 2026 14:34 UTC

DDOG, AMGN, MPWR, PLTR

Immediate term

Datadog and Palantir lead gains in early Friday trading while Amgen and Monolithic Power Systems face selling pressure. The session reflects fragmented movement across the tech-heavy index.

Datadog shares rose 5.1% in early trading
Amgen shares fell 5.7%, the worst in the Nasdaq 100
Palantir Technologies gained 4.8%
Monolithic Power Systems declined by 3.0%
Datadog's YTD return stands at 2.1%
Amgen's YTD return is down 0.2%

Early trading on Friday saw significant divergence among the components of the Nasdaq 100, with technology and healthcare stocks exhibiting opposing trends during the opening hours of the session. Datadog emerged as the top performer of the morning, with shares climbing 5.1%. This surge brings the company's year-to-date performance to a gain of 2.1%. Similarly, Palantir Technologies showed strong momentum, trading up 4.8% on the day. Conversely, Amgen lagged as the index's worst-performing constituent, with shares trading down 5.7%. This decline puts Amgen's year-to-date performance slightly in the red, down approximately 0.2%. Further downward movement was observed in Monolithic Power Systems, which traded down 3.0%. These shifts highlight the idiosyncratic nature of today's price action, as the index components move independently without a singular overarching catalyst.