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Earnings Score 65 Bearish

Delcath Systems Reports Disappointing Q3 Results Amid Clinical and Financial Challenges

Dec 16, 2025 15:25 UTC
DCTH

Delcath Systems (DCTH) saw its stock decline following a third-quarter report that revealed continued revenue shortfalls and setbacks in key clinical trial milestones. The biotech firm attributed the downturn to delayed regulatory feedback and lower-than-expected product sales.

  • Net loss widened to $14.2 million in Q3 2024, up from $9.8 million in Q3 2023
  • Revenue declined to $2.1 million, a 42% year-over-year decrease
  • Operating expenses increased to $16.5 million, primarily due to clinical trial and R&D costs
  • Phase 3 trial enrollment for mHAI system fell short of targets
  • FDA pre-submission meeting delayed, impacting potential regulatory pathway
  • Stock price dropped 28% following earnings release

Delcath Systems (DCTH) posted a net loss of $14.2 million for the third quarter of 2024, widening from a $9.8 million loss in the same period the prior year. Revenue dipped to $2.1 million, down 42% year-over-year, reflecting weak commercialization of its proprietary drug delivery platform, the Melphalan Hepatic Arterial Infusion (mHAI) system. The company cited insufficient patient enrollment in ongoing Phase 3 trials for the treatment of metastatic melanoma and liver cancer as a primary drag on progress. Regulatory delays from the U.S. Food and Drug Administration (FDA) on a pre-submission meeting for the mHAI system further hindered strategic momentum. Additionally, operating expenses rose to $16.5 million, driven by expanded clinical trial operations and increased R&D expenditures. The combined impact of declining sales and rising costs contributed to a 28% drop in share price within two trading days of the earnings release.

The information presented is derived from publicly available disclosures and financial reports related to Delcath Systems (DCTH). No proprietary or third-party data sources were used in the creation of this content.