A growing number of U.S. restaurants are launching specialized low-calorie, high-protein menus tailored to customers using weight-loss drugs like Ozempic and Wegovy. The trend reflects a significant shift in consumer behavior driven by pharmaceutical use, with over 200 restaurants now offering such options as of early 2026.
- Over 200 U.S. restaurants across 28 states have introduced 'Ozempic menus' as of early 2026.
- 12 million Americans received semaglutide-based prescriptions in 2025, driving dietary behavior changes.
- 41% of users of weight-loss drugs now seek low-calorie, high-protein meals when dining out.
- Menus feature dishes under 300 calories with at least 30g of protein, such as salmon bowls and egg white wraps.
- 54% of participating restaurants report a 17% increase in average check size during Q1 2026.
- Low-carb and high-protein ingredients saw a 22% year-over-year rise in restaurant procurement.
In a surprising culinary shift, more than 200 restaurants across 28 U.S. states have introduced dedicated 'Ozempic menus' since late 2025. These menus emphasize protein-rich, low-carbohydrate dishes designed to align with the dietary needs of individuals using GLP-1 receptor agonists such as semaglutide and tirzepatide. Chains including Sweetgreen, Panera Bread, and Sweetgreen’s regional partners have piloted these offerings in cities like Chicago, Austin, and Seattle. The movement stems from a surge in prescription use: over 12 million Americans were prescribed semaglutide-based medications in 2025, with 68% reporting changes in eating habits, including reduced appetite and increased focus on portion control. This behavioral shift has prompted restaurateurs to adapt. Data from a consumer survey conducted in January 2026 found that 41% of users of weight-loss drugs now dine out more frequently but seek meals with fewer than 300 calories and at least 30 grams of protein per serving. The new menus feature items like grilled salmon bowls with quinoa and roasted vegetables (285 calories, 35g protein), high-protein egg white wraps (260 calories, 32g protein), and plant-based protein salads with tahini dressing (310 calories, 34g protein). Some restaurants are also offering smaller portion sizes and customizable meal plans, with 54% reporting a 17% increase in average check size during the first quarter of 2026 due to upsells. The trend is not limited to chain restaurants—local establishments in Denver, Portland, and Miami have also launched similar initiatives, often in collaboration with dietitians. This adaptation reflects broader changes in food demand, with low-carb and protein-dense ingredients seeing a 22% year-over-year increase in restaurant procurement. The development may mark a long-term shift in how restaurants approach menu design, particularly as pharmaceutical weight management continues to gain mainstream traction.