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ABBV vs SPRO

ABBV
AbbVie Inc.
NEUTRAL
Price
$219.26
Market Cap
$387.52B
Sector
Healthcare
AI Confidence
68%
SPRO
Spero Therapeutics, Inc.
BEARISH
Price
$2.75
Market Cap
$159.2M
Sector
Healthcare
AI Confidence
85%

Valuation

P/E Ratio
ABBV
163.63
SPRO
18.33
Forward P/E
ABBV
15.42
SPRO
-2.48
P/B Ratio
ABBV
-146.66
SPRO
2.63
P/S Ratio
ABBV
6.5
SPRO
2.38
EV/EBITDA
ABBV
15.27
SPRO
17.01

Profitability

Gross Margin
ABBV
71.46%
SPRO
42.42%
Operating Margin
ABBV
35.5%
SPRO
76.05%
Profit Margin
ABBV
4.0%
SPRO
12.83%
ROE
ABBV
137.96%
SPRO
16.3%
ROA
ABBV
9.59%
SPRO
4.99%

Growth

Revenue Growth
ABBV
9.1%
SPRO
174.5%
Earnings Growth
ABBV
-88.7%
SPRO
--

Financial Health

Debt/Equity
ABBV
--
SPRO
0.05
Current Ratio
ABBV
0.72
SPRO
7.59
Quick Ratio
ABBV
0.47
SPRO
7.4

Dividends

Dividend Yield
ABBV
3.05%
SPRO
--
Payout Ratio
ABBV
490.15%
SPRO
0.0%

AI Verdict

ABBV NEUTRAL

The Advanced Deterministic Scorecard reveals a mixed health profile with a Piotroski F-Score of 4/9 indicating stable but not strong fundamentals, while the absence of an Altman Z-Score prevents a clear distress risk assessment. Despite robust operating margins and consistent revenue growth, the company faces significant headwinds from negative earnings growth, an extremely high P/E ratio, and a dangerously elevated payout ratio. Strong historical price performance and analyst buy sentiment are counterbalanced by bearish insider activity and deteriorating profitability trends. The stock appears to trade at a substantial premium to its intrinsic value, suggesting limited margin of safety.

Strengths
High operating margin (35.50%) indicating strong pricing power and cost control
Consistent revenue growth (9.10% YoY) outpacing sector average
Strong track record of earnings surprises (22 out of 25 quarters beat estimates)
Risks
Extremely high P/E ratio (163.63) vs forward P/E (15.42), suggesting potential overvaluation on trailing basis
Earnings growth collapsing (YoY: -88.70%, Q/Q: -88.10%) indicating severe profitability deterioration
Unsustainable dividend payout ratio (490.15%) threatening dividend security
SPRO BEARISH

SPRO exhibits a critical divergence between its explosive revenue growth and its underlying financial health, evidenced by a weak Piotroski F-Score of 2/9. While the company maintains a strong current ratio (7.59) and low debt, the current price of $2.75 trades at a significant premium to both its Graham Number ($1.88) and Intrinsic Value ($1.05). This valuation gap, combined with aggressive insider selling by the CEO and COO and a bearish technical trend, suggests the recent 1-year price surge is unsustainable. The negative forward P/E further indicates an expectation of returning to losses despite recent revenue spikes.

Strengths
Exceptional YoY revenue growth of 174.50%
Very high liquidity with a current ratio of 7.59
Minimal leverage with a Debt/Equity ratio of 0.05
Risks
Severe financial health deterioration indicated by Piotroski F-Score (2/9)
Strong bearish insider signal with multiple sales by CEO and COO
Significant overvaluation relative to Graham and Intrinsic value baselines

Compare Another Pair

ABBV vs SPRO: Head-to-Head Comparison

This page compares AbbVie Inc. (ABBV) and Spero Therapeutics, Inc. (SPRO) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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