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ACRS vs AZN

ACRS
Aclaris Therapeutics, Inc.
BEARISH
Price
$3.54
Market Cap
$428.6M
Sector
Healthcare
AI Confidence
87%
AZN
AstraZeneca PLC
NEUTRAL
Price
$92.95
Market Cap
$288.2B
Sector
Healthcare
AI Confidence
75%

Valuation

P/E Ratio
ACRS
--
AZN
30.48
Forward P/E
ACRS
-4.42
AZN
18.17
P/B Ratio
ACRS
4.14
AZN
3.14
P/S Ratio
ACRS
54.77
AZN
4.96
EV/EBITDA
ACRS
-4.57
AZN
8.26

Profitability

Gross Margin
ACRS
0.0%
AZN
83.26%
Operating Margin
ACRS
-1724.63%
AZN
24.11%
Profit Margin
ACRS
0.0%
AZN
16.17%
ROE
ACRS
-50.2%
AZN
21.67%
ROA
ACRS
-24.32%
AZN
9.06%

Growth

Revenue Growth
ACRS
-85.9%
AZN
12.0%
Earnings Growth
ACRS
--
AZN
78.0%

Financial Health

Debt/Equity
ACRS
0.02
AZN
0.71
Current Ratio
ACRS
3.36
AZN
0.88
Quick Ratio
ACRS
3.36
AZN
0.69

Dividends

Dividend Yield
ACRS
--
AZN
1.71%
Payout Ratio
ACRS
0.0%
AZN
51.99%

AI Verdict

ACRS BEARISH

ACRS exhibits severe financial distress despite a strong analyst consensus, as evidenced by a Piotroski F-Score of 1/9 indicating extreme weakness in operational and financial health. The company reports negative profitability across all key margins, with a staggering -1724.63% operating margin and a -50.20% ROE, signaling deep operational inefficiency. Although the debt-to-equity ratio is low (0.02) and liquidity is strong (current ratio 3.36), the company's revenue has collapsed by 85.9% YoY, and it continues to burn cash with no free cash flow. The absence of a Graham Number and intrinsic value estimate underscores the lack of a reliable valuation anchor, while the stock trades at an inflated Price/Sales of 54.77, suggesting extreme speculative pricing. Despite a recent 126.9% 1-year return, the underlying fundamentals remain critically deteriorating.

Strengths
Strong liquidity with current and quick ratios of 3.36
Low debt-to-equity ratio of 0.02, indicating minimal leverage risk
Analyst consensus of 'strong_buy' with a target price of $8.29
Risks
Piotroski F-Score of 1/9 indicates severe financial distress and operational failure
Revenue declined 85.9% YoY, signaling business contraction
Negative operating margin (-1724.63%) and ROE (-50.20%) reflect deep unprofitability
AZN NEUTRAL

AstraZeneca's deterministic health score is concerning with a Piotroski F-Score of 4/9, indicating marginal financial stability. While profitability metrics like ROE (21.67%) and gross margin (83.26%) are strong, the current price of $92.95 trades significantly above the Graham Number of $45.06, reflecting high growth expectations. Revenue and earnings growth are robust (12% and 78% YoY, respectively), but recent earnings surprises have been volatile, including a -25.9% miss in Q3 2025. Analysts maintain a strong_buy recommendation, though insider selling and weak technical trends (10/100) suggest caution near-term.

Strengths
Exceptional gross margin of 83.26% indicates strong pricing power and cost control
High ROE of 21.67% reflects efficient use of shareholder equity
Strong earnings growth of 78% YoY and solid revenue growth of 12% demonstrate momentum
Risks
Piotroski F-Score of 4/9 indicates weak financial health, particularly in liquidity and earnings consistency
Current Ratio of 0.88 and Quick Ratio of 0.69 signal potential short-term liquidity pressure
Earnings volatility with multiple recent misses, including a -25.9% surprise in Q3 2025

Compare Another Pair

ACRS vs AZN: Head-to-Head Comparison

This page compares Aclaris Therapeutics, Inc. (ACRS) and AstraZeneca PLC (AZN) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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