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ADAG vs AZN

ADAG
Adagene Inc.
BULLISH
Price
$4.13
Market Cap
$194.7M
Sector
Healthcare
AI Confidence
85%
AZN
AstraZeneca PLC
NEUTRAL
Price
$92.95
Market Cap
$288.2B
Sector
Healthcare
AI Confidence
75%

Valuation

P/E Ratio
ADAG
--
AZN
30.48
Forward P/E
ADAG
-5.74
AZN
18.17
P/B Ratio
ADAG
5.14
AZN
3.14
P/S Ratio
ADAG
1886.09
AZN
4.96
EV/EBITDA
ADAG
-5.72
AZN
8.26

Profitability

Gross Margin
ADAG
100.0%
AZN
83.26%
Operating Margin
ADAG
-32283.6%
AZN
24.11%
Profit Margin
ADAG
0.0%
AZN
16.17%
ROE
ADAG
-63.26%
AZN
21.67%
ROA
ADAG
-24.89%
AZN
9.06%

Growth

Revenue Growth
ADAG
--
AZN
12.0%
Earnings Growth
ADAG
--
AZN
78.0%

Financial Health

Debt/Equity
ADAG
0.18
AZN
0.71
Current Ratio
ADAG
2.29
AZN
0.88
Quick Ratio
ADAG
2.2
AZN
0.69

Dividends

Dividend Yield
ADAG
--
AZN
1.71%
Payout Ratio
ADAG
0.0%
AZN
51.99%

AI Verdict

ADAG BULLISH

ADAG's Piotroski F-Score of 4/9 indicates weak financial health, with negative profitability and high operating losses, but the company shows strong earnings surprise momentum and improving Q/Q EPS growth. Despite a lack of Altman Z-Score and Graham Number, the stock trades at a premium valuation (Price/Sales: 1886.09) due to high growth expectations in a sector with elevated average revenue growth. Insider sentiment is neutral, and analyst target price suggests significant upside potential. The recent 1-year return of +109.6% and strong quarterly beat rate support a bullish technical and earnings narrative.

Strengths
Strong earnings surprise history with 3 out of last 4 quarters beating estimates by an average of 39.09%
Improving Q/Q EPS growth of +58.3% and year-over-year EPS growth of +40.0%
High gross margin of 100.0% indicating strong product-level pricing power or low cost structure
Risks
Piotroski F-Score of 4/9 signals weak financial health, with negative ROE (-63.26%), ROA (-24.89%), and operating margin (-32,283.60%)
No positive operating cash flow or free cash flow; high reliance on external financing
Price/Sales ratio of 1886.09 is extremely elevated, indicating extreme growth premium
AZN NEUTRAL

AstraZeneca's deterministic health score is concerning with a Piotroski F-Score of 4/9, indicating marginal financial stability. While profitability metrics like ROE (21.67%) and gross margin (83.26%) are strong, the current price of $92.95 trades significantly above the Graham Number of $45.06, reflecting high growth expectations. Revenue and earnings growth are robust (12% and 78% YoY, respectively), but recent earnings surprises have been volatile, including a -25.9% miss in Q3 2025. Analysts maintain a strong_buy recommendation, though insider selling and weak technical trends (10/100) suggest caution near-term.

Strengths
Exceptional gross margin of 83.26% indicates strong pricing power and cost control
High ROE of 21.67% reflects efficient use of shareholder equity
Strong earnings growth of 78% YoY and solid revenue growth of 12% demonstrate momentum
Risks
Piotroski F-Score of 4/9 indicates weak financial health, particularly in liquidity and earnings consistency
Current Ratio of 0.88 and Quick Ratio of 0.69 signal potential short-term liquidity pressure
Earnings volatility with multiple recent misses, including a -25.9% surprise in Q3 2025

Compare Another Pair

ADAG vs AZN: Head-to-Head Comparison

This page compares Adagene Inc. (ADAG) and AstraZeneca PLC (AZN) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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