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AGEN vs HRTX

AGEN
Agenus Inc.
BEARISH
Price
$3.99
Market Cap
$144.2M
Sector
Healthcare
AI Confidence
85%
HRTX
Heron Therapeutics, Inc.
BEARISH
Price
$0.85
Market Cap
$160.8M
Sector
Healthcare
AI Confidence
85%

Valuation

P/E Ratio
AGEN
--
HRTX
--
Forward P/E
AGEN
-1.73
HRTX
1.67
P/B Ratio
AGEN
-0.48
HRTX
12.01
P/S Ratio
AGEN
1.35
HRTX
1.04
EV/EBITDA
AGEN
-2.94
HRTX
-1142.32

Profitability

Gross Margin
AGEN
0.08%
HRTX
72.64%
Operating Margin
AGEN
-16.08%
HRTX
0.09%
Profit Margin
AGEN
-32.92%
HRTX
-13.04%
ROE
AGEN
--
HRTX
--
ROA
AGEN
-16.66%
HRTX
-0.65%

Growth

Revenue Growth
AGEN
20.4%
HRTX
-0.5%
Earnings Growth
AGEN
--
HRTX
--

Financial Health

Debt/Equity
AGEN
--
HRTX
9.81
Current Ratio
AGEN
0.47
HRTX
2.48
Quick Ratio
AGEN
0.03
HRTX
1.42

Dividends

Dividend Yield
AGEN
--
HRTX
--
Payout Ratio
AGEN
0.0%
HRTX
0.0%

AI Verdict

AGEN BEARISH

AGEN's deterministic health scores are severely compromised: a Piotroski F-Score of 0/9 signals extreme financial distress, and the absence of an Altman Z-Score with negative profitability and liquidity ratios indicates high bankruptcy risk. Despite a 20.4% YoY revenue growth and recent EPS improvement, the company remains unprofitable with a -32.92% profit margin and negative ROA. The stock trades at a price/sales of 1.35, but with no intrinsic value or Graham Number, it lacks a fundamental floor. Analysts' target price of $12.33 is not supported by current fundamentals, suggesting overvaluation based on speculative growth expectations.

Strengths
20.4% year-over-year revenue growth indicates top-line expansion
Recent quarterly EPS growth of +68.1% Q/Q and +81.9% YoY shows improving earnings trajectory
Positive earnings surprise in Q1 2026 (+64.8%) suggests potential operational improvement
Risks
Piotroski F-Score of 0/9 indicates severe financial deterioration and operational instability
Negative ROA (-16.66%) and gross margin (0.08%) reflect deep profitability issues
Extremely weak liquidity: current ratio of 0.47 and quick ratio of 0.03 signal imminent cash flow stress
HRTX BEARISH

HRTX presents a high-risk profile characterized by a stable but mediocre Piotroski F-Score of 4/9 and a complete lack of positive technical momentum (0/100). While the company maintains strong gross margins (72.64%) and a healthy current ratio (2.48), these are overshadowed by an extreme Debt/Equity ratio of 9.81 and a catastrophic 5-year price decline of 94.8%. There is a severe disconnect between the 'Strong Buy' analyst consensus with a $4.33 target and the actual market performance and fundamental leverage.

Strengths
Strong Gross Margin of 72.64%
Healthy liquidity with a Current Ratio of 2.48
Operating margin is near break-even (0.09%)
Risks
Extreme leverage with Debt/Equity at 9.81
Severe long-term value destruction (5Y Change: -94.8%)
Stagnant revenue growth (-0.50% YoY)

Compare Another Pair

AGEN vs HRTX: Head-to-Head Comparison

This page compares Agenus Inc. (AGEN) and Heron Therapeutics, Inc. (HRTX) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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