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ANAB vs AZN

ANAB
AnaptysBio, Inc.
BULLISH
Price
$64.81
Market Cap
$1.86B
Sector
Healthcare
AI Confidence
87%
AZN
AstraZeneca PLC
NEUTRAL
Price
$92.95
Market Cap
$288.2B
Sector
Healthcare
AI Confidence
75%

Valuation

P/E Ratio
ANAB
--
AZN
30.48
Forward P/E
ANAB
-16.06
AZN
18.17
P/B Ratio
ANAB
48.8
AZN
3.14
P/S Ratio
ANAB
7.94
AZN
4.96
EV/EBITDA
ANAB
38.02
AZN
8.26

Profitability

Gross Margin
ANAB
42.04%
AZN
83.26%
Operating Margin
ANAB
61.8%
AZN
24.11%
Profit Margin
ANAB
-5.64%
AZN
16.17%
ROE
ANAB
-24.49%
AZN
21.67%
ROA
ANAB
7.06%
AZN
9.06%

Growth

Revenue Growth
ANAB
151.1%
AZN
12.0%
Earnings Growth
ANAB
--
AZN
78.0%

Financial Health

Debt/Equity
ANAB
7.81
AZN
0.71
Current Ratio
ANAB
9.07
AZN
0.88
Quick Ratio
ANAB
8.95
AZN
0.69

Dividends

Dividend Yield
ANAB
--
AZN
1.71%
Payout Ratio
ANAB
0.0%
AZN
51.99%

AI Verdict

ANAB BULLISH

ANAB's Advanced Deterministic Scorecard reveals a weak financial health profile with a Piotroski F-Score of 2/9, indicating significant distress risk, and no Altman Z-Score available, which raises red flags for solvency. Despite this, the company exhibits extraordinary growth momentum with 151% YoY revenue growth and a stellar 319.4% YoY EPS growth, supported by consistent earnings beat rates and large positive surprises. The stock trades at a premium valuation (Price/Sales: 7.94, Price/Book: 48.80), but this is justified by its high-growth biotech profile and strong analyst consensus. Insider selling activity is bearish, but the magnitude of recent earnings upside and market momentum suggest underlying strength. The overall picture reflects a high-risk, high-reward speculative opportunity.

Strengths
Exceptional 151.10% YoY revenue growth and 319.4% YoY EPS growth
Strong earnings beat rate (3/4 in last 4 quarters) with average surprise of 75.37%
High operating margin (61.80%) despite negative net profit margin
Risks
Piotroski F-Score of 2/9 indicates severe financial distress and weak operational health
Debt/Equity ratio of 7.81 is extremely high, signaling financial leverage risk
Negative ROE (-24.49%) and negative net profit margin (-5.64%) despite strong operating performance
AZN NEUTRAL

AstraZeneca's deterministic health score is concerning with a Piotroski F-Score of 4/9, indicating marginal financial stability. While profitability metrics like ROE (21.67%) and gross margin (83.26%) are strong, the current price of $92.95 trades significantly above the Graham Number of $45.06, reflecting high growth expectations. Revenue and earnings growth are robust (12% and 78% YoY, respectively), but recent earnings surprises have been volatile, including a -25.9% miss in Q3 2025. Analysts maintain a strong_buy recommendation, though insider selling and weak technical trends (10/100) suggest caution near-term.

Strengths
Exceptional gross margin of 83.26% indicates strong pricing power and cost control
High ROE of 21.67% reflects efficient use of shareholder equity
Strong earnings growth of 78% YoY and solid revenue growth of 12% demonstrate momentum
Risks
Piotroski F-Score of 4/9 indicates weak financial health, particularly in liquidity and earnings consistency
Current Ratio of 0.88 and Quick Ratio of 0.69 signal potential short-term liquidity pressure
Earnings volatility with multiple recent misses, including a -25.9% surprise in Q3 2025

Compare Another Pair

ANAB vs AZN: Head-to-Head Comparison

This page compares AnaptysBio, Inc. (ANAB) and AstraZeneca PLC (AZN) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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