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AZN vs LGND

AZN
AstraZeneca PLC
NEUTRAL
Price
$92.95
Market Cap
$288.2B
Sector
Healthcare
AI Confidence
75%
LGND
Ligand Pharmaceuticals Incorporated
NEUTRAL
Price
$204.92
Market Cap
$4.09B
Sector
Healthcare
AI Confidence
85%

Valuation

P/E Ratio
AZN
30.48
LGND
33.43
Forward P/E
AZN
18.17
LGND
20.7
P/B Ratio
AZN
3.14
LGND
3.98
P/S Ratio
AZN
4.96
LGND
15.24
EV/EBITDA
AZN
8.26
LGND
46.98

Profitability

Gross Margin
AZN
83.26%
LGND
64.29%
Operating Margin
AZN
24.11%
LGND
33.59%
Profit Margin
AZN
16.17%
LGND
46.42%
ROE
AZN
21.67%
LGND
13.47%
ROA
AZN
9.06%
LGND
2.36%

Growth

Revenue Growth
AZN
12.0%
LGND
39.4%
Earnings Growth
AZN
78.0%
LGND
--

Financial Health

Debt/Equity
AZN
0.71
LGND
0.44
Current Ratio
AZN
0.88
LGND
22.23
Quick Ratio
AZN
0.69
LGND
21.83

Dividends

Dividend Yield
AZN
1.71%
LGND
--
Payout Ratio
AZN
51.99%
LGND
0.0%

AI Verdict

AZN NEUTRAL

AstraZeneca's deterministic health score is concerning with a Piotroski F-Score of 4/9, indicating marginal financial stability. While profitability metrics like ROE (21.67%) and gross margin (83.26%) are strong, the current price of $92.95 trades significantly above the Graham Number of $45.06, reflecting high growth expectations. Revenue and earnings growth are robust (12% and 78% YoY, respectively), but recent earnings surprises have been volatile, including a -25.9% miss in Q3 2025. Analysts maintain a strong_buy recommendation, though insider selling and weak technical trends (10/100) suggest caution near-term.

Strengths
Exceptional gross margin of 83.26% indicates strong pricing power and cost control
High ROE of 21.67% reflects efficient use of shareholder equity
Strong earnings growth of 78% YoY and solid revenue growth of 12% demonstrate momentum
Risks
Piotroski F-Score of 4/9 indicates weak financial health, particularly in liquidity and earnings consistency
Current Ratio of 0.88 and Quick Ratio of 0.69 signal potential short-term liquidity pressure
Earnings volatility with multiple recent misses, including a -25.9% surprise in Q3 2025
LGND NEUTRAL

LGND presents a dichotomy between exceptional operational profitability and poor deterministic health/value scores. While the company boasts a massive 46.42% profit margin and strong revenue growth (39.4%), the Piotroski F-Score of 3/9 indicates weak financial trend momentum. The stock is trading at a significant premium to its Graham Number ($84.23) and Intrinsic Value ($42.91), suggesting the market is pricing in aggressive future growth. Bearish insider activity and a weak technical trend further temper the outlook despite strong analyst target prices.

Strengths
Exceptional profit margins (46.42%) and gross margins (64.29%)
Strong top-line growth with 39.40% YoY revenue increase
Extremely high liquidity indicated by a Current Ratio of 22.23
Risks
Severe overvaluation relative to Graham and Intrinsic value benchmarks
Weak financial health trend as evidenced by a Piotroski F-Score of 3/9
Bearish insider sentiment with 9 sell transactions and 0 buys

Compare Another Pair

AZN vs LGND: Head-to-Head Comparison

This page compares AstraZeneca PLC (AZN) and Ligand Pharmaceuticals Incorporated (LGND) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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