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JNJ vs LYEL

JNJ
Johnson & Johnson
NEUTRAL
Price
$237.96
Market Cap
$573.46B
Sector
Healthcare
AI Confidence
85%
LYEL
Lyell Immunopharma, Inc.
BEARISH
Price
$24.80
Market Cap
$578.5M
Sector
Healthcare
AI Confidence
85%

Valuation

P/E Ratio
JNJ
21.55
LYEL
--
Forward P/E
JNJ
18.9
LYEL
-29.52
P/B Ratio
JNJ
7.03
LYEL
2.12
P/S Ratio
JNJ
6.09
LYEL
16070.7
EV/EBITDA
JNJ
17.81
LYEL
-2.06

Profitability

Gross Margin
JNJ
68.08%
LYEL
100.0%
Operating Margin
JNJ
23.97%
LYEL
-1024630.0%
Profit Margin
JNJ
28.46%
LYEL
0.0%
ROE
JNJ
35.03%
LYEL
-86.98%
ROA
JNJ
8.68%
LYEL
-29.83%

Growth

Revenue Growth
JNJ
9.1%
LYEL
-45.5%
Earnings Growth
JNJ
48.6%
LYEL
--

Financial Health

Debt/Equity
JNJ
0.6
LYEL
0.21
Current Ratio
JNJ
1.03
LYEL
5.28
Quick Ratio
JNJ
0.69
LYEL
5.0

Dividends

Dividend Yield
JNJ
2.19%
LYEL
--
Payout Ratio
JNJ
46.6%
LYEL
0.0%

AI Verdict

JNJ NEUTRAL

JNJ presents a dichotomy between strong profitability and deteriorating fundamental health, evidenced by a weak Piotroski F-Score of 3/9. While the company maintains an impressive ROE of 35.03% and a consistent history of earnings beats, the current price of $237.96 trades at a significant premium to its Graham Number of $91.72. Growth remains robust on a YoY basis, but bearish insider sentiment and a very weak technical trend (10/100) suggest immediate headwinds. The stock is fundamentally sound in terms of earnings power but shows signs of operational inefficiency or declining quality in its deterministic health metrics.

Strengths
Exceptional Return on Equity (ROE) of 35.03%
Strong profit margins (28.46%) and gross margins (68.08%)
Consistent earnings beat track record over 25 quarters
Risks
Weak Piotroski F-Score (3/9) indicating declining fundamental health
Bearish insider activity with $58.35M in net sales and zero buys
Low liquidity indicated by a Quick Ratio of 0.69
LYEL BEARISH

LYEL exhibits critical financial weakness, highlighted by a Piotroski F-Score of 1/9, indicating severe deterioration in fundamental health. Despite a speculative 1-year price rally of 178.7%, the company suffers from extreme operating losses (-1,024,633% margin) and negative revenue growth (-45.50%). The valuation is disconnected from fundamentals, evidenced by an astronomical Price/Sales ratio, while insider sentiment remains bearish with consistent selling by top executives.

Strengths
Strong short-term liquidity with a Current Ratio of 5.28
Low leverage with a Debt/Equity ratio of 0.21
Positive analyst sentiment with a mean target price of $34.80
Risks
Critical financial health as indicated by a 1/9 Piotroski F-Score
Extreme cash burn and negative operating margins
Negative revenue growth (-45.50% YoY) and EPS contraction

Compare Another Pair

JNJ vs LYEL: Head-to-Head Comparison

This page compares Johnson & Johnson (JNJ) and Lyell Immunopharma, Inc. (LYEL) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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