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JNJ vs PRME

JNJ
Johnson & Johnson
NEUTRAL
Price
$237.96
Market Cap
$573.46B
Sector
Healthcare
AI Confidence
85%
PRME
Prime Medicine, Inc.
BEARISH
Price
$3.81
Market Cap
$687.9M
Sector
Healthcare
AI Confidence
85%

Valuation

P/E Ratio
JNJ
21.55
PRME
--
Forward P/E
JNJ
18.9
PRME
-4.78
P/B Ratio
JNJ
7.03
PRME
5.58
P/S Ratio
JNJ
6.09
PRME
148.51
EV/EBITDA
JNJ
17.81
PRME
-3.05

Profitability

Gross Margin
JNJ
68.08%
PRME
0.0%
Operating Margin
JNJ
23.97%
PRME
-5800.48%
Profit Margin
JNJ
28.46%
PRME
0.0%
ROE
JNJ
35.03%
PRME
-146.81%
ROA
JNJ
8.68%
PRME
-40.68%

Growth

Revenue Growth
JNJ
9.1%
PRME
-61.6%
Earnings Growth
JNJ
48.6%
PRME
--

Financial Health

Debt/Equity
JNJ
0.6
PRME
0.96
Current Ratio
JNJ
1.03
PRME
4.84
Quick Ratio
JNJ
0.69
PRME
4.75

Dividends

Dividend Yield
JNJ
2.19%
PRME
--
Payout Ratio
JNJ
46.6%
PRME
0.0%

AI Verdict

JNJ NEUTRAL

JNJ presents a dichotomy between strong profitability and deteriorating fundamental health, evidenced by a weak Piotroski F-Score of 3/9. While the company maintains an impressive ROE of 35.03% and a consistent history of earnings beats, the current price of $237.96 trades at a significant premium to its Graham Number of $91.72. Growth remains robust on a YoY basis, but bearish insider sentiment and a very weak technical trend (10/100) suggest immediate headwinds. The stock is fundamentally sound in terms of earnings power but shows signs of operational inefficiency or declining quality in its deterministic health metrics.

Strengths
Exceptional Return on Equity (ROE) of 35.03%
Strong profit margins (28.46%) and gross margins (68.08%)
Consistent earnings beat track record over 25 quarters
Risks
Weak Piotroski F-Score (3/9) indicating declining fundamental health
Bearish insider activity with $58.35M in net sales and zero buys
Low liquidity indicated by a Quick Ratio of 0.69
PRME BEARISH

PRME exhibits severe financial distress from a deterministic standpoint, highlighted by a Piotroski F-Score of 1/9, indicating critical weakness in profitability and efficiency. While the company maintains a strong liquidity cushion with a current ratio of 4.84, it is characterized by an extreme cash burn rate and an unsustainable Price-to-Sales ratio of 148.51. Despite bullish analyst targets and a recent 1-year price surge, the fundamental data shows declining revenue growth (-61.6%) and deep operating losses. The stock remains a high-risk speculative biotech play with no current path to intrinsic value based on traditional metrics.

Strengths
Strong short-term liquidity (Current Ratio: 4.84)
Positive analyst sentiment with a target price of $6.92
Recent 1-year price recovery (+207.3%)
Risks
Extreme operating losses (Operating Margin: -5800.48%)
Severe revenue contraction (YoY Growth: -61.60%)
Astronomical valuation relative to sales (P/S: 148.51)

Compare Another Pair

JNJ vs PRME: Head-to-Head Comparison

This page compares Johnson & Johnson (JNJ) and Prime Medicine, Inc. (PRME) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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