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JNJ vs SPRO

JNJ
Johnson & Johnson
NEUTRAL
Price
$237.96
Market Cap
$573.46B
Sector
Healthcare
AI Confidence
85%
SPRO
Spero Therapeutics, Inc.
BEARISH
Price
$2.75
Market Cap
$159.2M
Sector
Healthcare
AI Confidence
85%

Valuation

P/E Ratio
JNJ
21.55
SPRO
18.33
Forward P/E
JNJ
18.9
SPRO
-2.48
P/B Ratio
JNJ
7.03
SPRO
2.63
P/S Ratio
JNJ
6.09
SPRO
2.38
EV/EBITDA
JNJ
17.81
SPRO
17.01

Profitability

Gross Margin
JNJ
68.08%
SPRO
42.42%
Operating Margin
JNJ
23.97%
SPRO
76.05%
Profit Margin
JNJ
28.46%
SPRO
12.83%
ROE
JNJ
35.03%
SPRO
16.3%
ROA
JNJ
8.68%
SPRO
4.99%

Growth

Revenue Growth
JNJ
9.1%
SPRO
174.5%
Earnings Growth
JNJ
48.6%
SPRO
--

Financial Health

Debt/Equity
JNJ
0.6
SPRO
0.05
Current Ratio
JNJ
1.03
SPRO
7.59
Quick Ratio
JNJ
0.69
SPRO
7.4

Dividends

Dividend Yield
JNJ
2.19%
SPRO
--
Payout Ratio
JNJ
46.6%
SPRO
0.0%

AI Verdict

JNJ NEUTRAL

JNJ presents a dichotomy between strong profitability and deteriorating fundamental health, evidenced by a weak Piotroski F-Score of 3/9. While the company maintains an impressive ROE of 35.03% and a consistent history of earnings beats, the current price of $237.96 trades at a significant premium to its Graham Number of $91.72. Growth remains robust on a YoY basis, but bearish insider sentiment and a very weak technical trend (10/100) suggest immediate headwinds. The stock is fundamentally sound in terms of earnings power but shows signs of operational inefficiency or declining quality in its deterministic health metrics.

Strengths
Exceptional Return on Equity (ROE) of 35.03%
Strong profit margins (28.46%) and gross margins (68.08%)
Consistent earnings beat track record over 25 quarters
Risks
Weak Piotroski F-Score (3/9) indicating declining fundamental health
Bearish insider activity with $58.35M in net sales and zero buys
Low liquidity indicated by a Quick Ratio of 0.69
SPRO BEARISH

SPRO exhibits a critical divergence between its explosive revenue growth and its underlying financial health, evidenced by a weak Piotroski F-Score of 2/9. While the company maintains a strong current ratio (7.59) and low debt, the current price of $2.75 trades at a significant premium to both its Graham Number ($1.88) and Intrinsic Value ($1.05). This valuation gap, combined with aggressive insider selling by the CEO and COO and a bearish technical trend, suggests the recent 1-year price surge is unsustainable. The negative forward P/E further indicates an expectation of returning to losses despite recent revenue spikes.

Strengths
Exceptional YoY revenue growth of 174.50%
Very high liquidity with a current ratio of 7.59
Minimal leverage with a Debt/Equity ratio of 0.05
Risks
Severe financial health deterioration indicated by Piotroski F-Score (2/9)
Strong bearish insider signal with multiple sales by CEO and COO
Significant overvaluation relative to Graham and Intrinsic value baselines

Compare Another Pair

JNJ vs SPRO: Head-to-Head Comparison

This page compares Johnson & Johnson (JNJ) and Spero Therapeutics, Inc. (SPRO) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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