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KPTI vs LLY

KPTI
Karyopharm Therapeutics Inc.
BEARISH
Price
$8.00
Market Cap
$180.3M
Sector
Healthcare
AI Confidence
90%
LLY
Eli Lilly and Company
NEUTRAL
Price
$958.65
Market Cap
$858.01B
Sector
Healthcare
AI Confidence
85%

Valuation

P/E Ratio
KPTI
--
LLY
41.7
Forward P/E
KPTI
-1.83
LLY
22.78
P/B Ratio
KPTI
-0.5
LLY
32.33
P/S Ratio
KPTI
1.23
LLY
13.16
EV/EBITDA
KPTI
-4.3
LLY
27.08

Profitability

Gross Margin
KPTI
9.93%
LLY
83.04%
Operating Margin
KPTI
-52.36%
LLY
44.9%
Profit Margin
KPTI
-134.21%
LLY
31.67%
ROE
KPTI
--
LLY
101.16%
ROA
KPTI
-41.56%
LLY
19.41%

Growth

Revenue Growth
KPTI
11.6%
LLY
42.6%
Earnings Growth
KPTI
--
LLY
51.4%

Financial Health

Debt/Equity
KPTI
--
LLY
1.65
Current Ratio
KPTI
1.12
LLY
1.58
Quick Ratio
KPTI
0.98
LLY
0.78

Dividends

Dividend Yield
KPTI
--
LLY
0.68%
Payout Ratio
KPTI
0.0%
LLY
26.14%

AI Verdict

KPTI BEARISH

KPTI exhibits severe financial distress, highlighted by a critical Piotroski F-Score of 1/9 and a negative Price-to-Book ratio of -0.50, indicating negative shareholder equity. While the stock has seen a speculative 1-year price surge of 100.5%, the underlying fundamentals are catastrophic with a profit margin of -134.21% and a consistent track record of missing earnings estimates (0/4 in the last year). Despite bullish analyst targets, the combination of insider selling and extreme operational inefficiency suggests a high risk of further capital erosion.

Strengths
Positive year-over-year revenue growth of 11.60%
Recent 1-year price recovery (+100.5%)
Improving EPS growth trend (+38.1% YoY), though still deeply negative
Risks
Negative Book Value (P/B -0.50) indicating insolvency risk
Extreme operational losses (Profit Margin -134.21%)
Critical Piotroski F-Score (1/9) signaling fundamental weakness
LLY NEUTRAL

LLY shows neutral fundamentals based on deterministic rules. Financial strength is weak (F-Score 3/9). Mixed signals with both opportunities and risks present.

Strengths
Strong profitability (31.7% margin)
Strong revenue growth of 42.6%
Strong ROE of 101.2%
Risks
High valuation with P/E of 41.7
Premium vs Graham Number ($123.85)
Weak financial trend (Piotroski F-Score: 3/9)

Compare Another Pair

KPTI vs LLY: Head-to-Head Comparison

This page compares Karyopharm Therapeutics Inc. (KPTI) and Eli Lilly and Company (LLY) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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