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ASND vs AZN

ASND
Ascendis Pharma A/S
BULLISH
Price
$225.98
Market Cap
$13.87B
Sector
Healthcare
AI Confidence
85%
AZN
AstraZeneca PLC
NEUTRAL
Price
$92.95
Market Cap
$288.2B
Sector
Healthcare
AI Confidence
75%

Valuation

P/E Ratio
ASND
--
AZN
30.48
Forward P/E
ASND
17.77
AZN
18.17
P/B Ratio
ASND
-73.94
AZN
3.14
P/S Ratio
ASND
19.27
AZN
4.96
EV/EBITDA
ASND
-107.5
AZN
8.26

Profitability

Gross Margin
ASND
86.82%
AZN
83.26%
Operating Margin
ASND
0.97%
AZN
24.11%
Profit Margin
ASND
-31.67%
AZN
16.17%
ROE
ASND
--
AZN
21.67%
ROA
ASND
-6.86%
AZN
9.06%

Growth

Revenue Growth
ASND
42.3%
AZN
12.0%
Earnings Growth
ASND
--
AZN
78.0%

Financial Health

Debt/Equity
ASND
--
AZN
0.71
Current Ratio
ASND
1.04
AZN
0.88
Quick Ratio
ASND
0.72
AZN
0.69

Dividends

Dividend Yield
ASND
--
AZN
1.71%
Payout Ratio
ASND
0.0%
AZN
51.99%

AI Verdict

ASND BULLISH

ASND's Piotroski F-Score of 2/9 indicates weak financial health, with significant red flags in profitability and cash flow, while the absence of an Altman Z-Score raises concern about long-term solvency. Despite this, the company exhibits strong revenue growth (42.3% YoY) and a robust gross margin (86.82%), supported by a high analyst consensus of 'strong_buy' and a target price of $282.19. The stock trades at a premium valuation (Price/Sales: 19.27, Forward P/E: 17.77), reflecting market confidence in its growth trajectory rather than current profitability. Insider sentiment is neutral (40/100), suggesting cautious optimism, while technical trends remain bearish, indicating short-term weakness.

Strengths
Strong revenue growth of 42.3% YoY, outpacing sector average
Exceptional gross margin of 86.82%, indicating pricing power and efficient production
High analyst consensus with 16 analysts rating 'strong_buy' and a target price of $282.19
Risks
Piotroski F-Score of 2/9 signals severe financial distress, with negative ROA, low operating margin, and lack of profitability
Negative profit margin (-31.67%) and negative ROE indicate ongoing losses despite revenue growth
Absence of key financial metrics (Debt/Equity, Cash, FCF) limits assessment of balance sheet strength
AZN NEUTRAL

AstraZeneca's deterministic health score is concerning with a Piotroski F-Score of 4/9, indicating marginal financial stability. While profitability metrics like ROE (21.67%) and gross margin (83.26%) are strong, the current price of $92.95 trades significantly above the Graham Number of $45.06, reflecting high growth expectations. Revenue and earnings growth are robust (12% and 78% YoY, respectively), but recent earnings surprises have been volatile, including a -25.9% miss in Q3 2025. Analysts maintain a strong_buy recommendation, though insider selling and weak technical trends (10/100) suggest caution near-term.

Strengths
Exceptional gross margin of 83.26% indicates strong pricing power and cost control
High ROE of 21.67% reflects efficient use of shareholder equity
Strong earnings growth of 78% YoY and solid revenue growth of 12% demonstrate momentum
Risks
Piotroski F-Score of 4/9 indicates weak financial health, particularly in liquidity and earnings consistency
Current Ratio of 0.88 and Quick Ratio of 0.69 signal potential short-term liquidity pressure
Earnings volatility with multiple recent misses, including a -25.9% surprise in Q3 2025

Compare Another Pair

ASND vs AZN: Head-to-Head Comparison

This page compares Ascendis Pharma A/S (ASND) and AstraZeneca PLC (AZN) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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