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ASND

BULLISH
$225.98 Live
Ascendis Pharma A/S · NASDAQ
Target $282.19 (+24.9%)
$124.06 52W Range $248.6

At a glance

Key valuation, profitability, growth, and risk metrics.

Updated Mar 14, 2026
Market cap
$13.87B
P/E
N/A
ROE
N/A
Profit margin
-31.7%
Debt/Equity
N/A
Dividend yield
N/A

AI Analysis

AI-powered fundamental assessment

Confidence
85%
ASND's Piotroski F-Score of 2/9 indicates weak financial health, with significant red flags in profitability and cash flow, while the absence of an Altman Z-Score raises concern about long-term solvency. Despite this, the company exhibits strong revenue growth (42.3% YoY) and a robust gross margin (86.82%), supported by a high analyst consensus of 'strong_buy' and a target price of $282.19. The stock trades at a premium valuation (Price/Sales: 19.27, Forward P/E: 17.77), reflecting market confidence in its growth trajectory rather than current profitability. Insider sentiment is neutral (40/100), suggesting cautious optimism, while technical trends remain bearish, indicating short-term weakness.

Key Strengths

Strong revenue growth of 42.3% YoY, outpacing sector average
Exceptional gross margin of 86.82%, indicating pricing power and efficient production
High analyst consensus with 16 analysts rating 'strong_buy' and a target price of $282.19
Significant 5-year stock appreciation (+53.7%) and strong 1-year return (+48.4%)
Positive peer benchmarking against biotech peers with similar growth profiles

Key Risks

Piotroski F-Score of 2/9 signals severe financial distress, with negative ROA, low operating margin, and lack of profitability
Negative profit margin (-31.67%) and negative ROE indicate ongoing losses despite revenue growth
Absence of key financial metrics (Debt/Equity, Cash, FCF) limits assessment of balance sheet strength
Price/Book ratio of -73.94 suggests overvaluation relative to book value, likely due to intangible-heavy balance sheet
Technical trend is bearish (10/100), indicating short-term downward momentum despite long-term upside
AI Fair Value Estimate
Based on comprehensive analysis
$245.0
+8.4% above current price

Performance Snowflake

Multi-dimensional analysis across 5 key categories

Overall
50
Moderate
Value
58
Future
85
Past
70
Health
35
Dividend
0
AI Verdict
cautiously bullish
Key drivers: High revenue growth and strong gross margins, Positive analyst sentiment and target price upside, Market leadership in biotech growth segment
Confidence
85%
Value
58/100

Stock trades at a premium to book value and lacks traditional valuation anchors, but forward P/E is relatively attractive given growth expectations

Positives
  • Forward P/E of 17.77 is below sector average (164.56)
  • Price/Sales of 19.27 is elevated but justified by growth profile
Watchpoints
  • No Graham Number or intrinsic value formula available
  • Negative ROE and profit margin undermine traditional valuation models
Future
85/100

Growth metrics are among the strongest in the sector, though profitability remains a concern

Positives
  • 42.3% YoY revenue growth is exceptional
  • High growth trajectory aligns with biotech sector leadership
Watchpoints
  • No earnings growth data available
  • Sustainability of growth depends on R&D success and commercialization
Past
70/100

Historical performance is strong, but financial health metrics show deterioration

Positives
  • 5-year stock return of +53.7% and 3-year return of +106.6%
  • Consistent outperformance vs. sector peers
Watchpoints
  • Negative ROA (-6.86%) and declining profitability trends
  • Lack of consistent cash flow generation
Health
35/100

Financial health is weak; the low Piotroski score reflects poor profitability, negative ROA, and lack of cash flow

Positives
  • Current ratio of 1.04 suggests short-term liquidity is adequate
  • Quick ratio of 0.72 indicates some liquidity pressure but not critical
Watchpoints
  • Piotroski F-Score of 2/9 is extremely low, signaling financial distress
  • No Altman Z-Score available, but low F-Score implies distress risk
Dividend
0/100

Company is reinvesting all capital into growth; no dividend income potential

Positives
No standout positives identified.
Watchpoints
  • No dividend yield or payout ratio
  • Dividend strength is 0/100, indicating no dividend policy

Stock Price & Analyst Targets

Real-time price movements and analyst price targets

Current Price
$225.98
Analyst Target
$282.19
Upside/Downside
+24.9%

Multi-Horizon Performance vs Peers

Price momentum across 5Y → 1W horizons for ASND and closest competitors.

Updated 2026-03-13
ASN
Ascendis Pharma A/S
Primary
5Y
+53.7%
3Y
+106.6%
1Y
+48.4%
6M
+15.5%
1M
+2.0%
1W
-6.1%
RGC
Regencell Bioscience Holdings Limited
Peer
5Y
+10275.8%
3Y
+3861.7%
1Y
+3641.3%
6M
+64.7%
1M
+8.7%
1W
-0.5%
POD
Insulet Corporation
Peer
5Y
-28.4%
3Y
-37.3%
1Y
-19.6%
6M
-36.3%
1M
-12.6%
1W
+1.0%
NBI
Neurocrine Biosciences, Inc.
Peer
5Y
+34.2%
3Y
+30.1%
1Y
+19.1%
6M
-6.2%
1M
-0.5%
1W
+3.0%
MED
Medpace Holdings, Inc.
Peer
5Y
+174.6%
3Y
+172.4%
1Y
+78.2%
6M
-5.6%
1M
+12.7%
1W
-1.0%

Positive values indicate cumulative gains over the specified period. Comparables pulled from the same sector to highlight whether momentum is stock-specific or industry-wide.

Historical Performance Trends

Long-term financial metrics and growth patterns

Revenue & Net Income

Profit & Operating Margins

Return on Equity (ROE)

Quarterly Revenue Growth

Historical data shows last 12 quarters (3 years)

Valuation Metrics

Key valuation ratios and pricing indicators

P/E Ratio
N/A
Forward P/E
17.77
PEG Ratio
N/A
P/B Ratio
-73.94
P/S Ratio
19.27
EV/Revenue
19.62
EV/EBITDA
-107.5
Market Cap
$13.87B

Profitability

Profit margins and return metrics

Profit Margin -31.67%
Operating Margin 0.97%
Gross Margin 86.82%
ROE N/A
ROA -6.86%

Growth

Revenue and earnings growth rates

Revenue Growth +42.3%
Earnings Growth N/A
Q/Q Revenue Growth N/A
Q/Q Earnings Growth N/A

Financial Health

Balance sheet strength and liquidity metrics

Debt/Equity
N/A
Current Ratio
1.04
Good
Quick Ratio
0.72
Poor
Cash/Share
$10.04

Financial Statement Flow

Interactive flow visualization showing how money moves through the company Q4 2025

Revenue
$0.2B
Gross Margin
90.5%
Op. Margin
2.6%
Net Margin
-13.6%
Total Assets
$1.3B
Liabilities
$1.5B
Equity
$-0.2B
Debt/Equity
-9.00x
Operating CF
$0.1B
CapEx
$-0.0B
Free Cash Flow
$0.1B
FCF Yield
95%

Healthcare Sector Comparison

Comparing ASND against 560 companies in the Healthcare sector (34 bullish, 167 neutral, 359 bearish)
Profit Margin
-31.67%
This Stock
vs
-16.28%
Sector Avg
+94.5% (Superior)
Revenue Growth
42.3%
This Stock
vs
124.04%
Sector Avg
-65.9% (Slower)
Current Ratio
1.04
This Stock
vs
4.47
Sector Avg
-76.8% (Weaker)

Similar Companies

Peer comparison within the same industry

Wall Street Analysts

Professional analyst ratings and price targets

Consensus
STRONG_BUY
16 analysts
RBC Capital
2026-03-03
Maintains
Outperform Outperform
Oppenheimer
2026-02-12
Maintains
Outperform Outperform
Wedbush
2026-02-12
Maintains
Outperform Outperform
B of A Securities
2026-01-30
Maintains
Buy Buy
Barclays
2026-01-28
init
Overweight
RBC Capital
2026-01-20
Maintains
Outperform Outperform
Wells Fargo
2026-01-20
Maintains
Overweight Overweight
Wells Fargo
2026-01-09
Maintains
Overweight Overweight
TD Cowen
2026-01-07
reit
Buy Buy
Stifel
2025-12-11
Maintains
Buy Buy

Past News Coverage

Recent headlines mentioning ASND from our newsroom.

Newest → oldest
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