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ATHE vs AZN

ATHE
Alterity Therapeutics Limited
BEARISH
Price
$3.55
Market Cap
$64.3M
Sector
Healthcare
AI Confidence
65%
AZN
AstraZeneca PLC
NEUTRAL
Price
$92.95
Market Cap
$288.2B
Sector
Healthcare
AI Confidence
75%

Valuation

P/E Ratio
ATHE
--
AZN
30.48
Forward P/E
ATHE
-4.49
AZN
18.17
P/B Ratio
ATHE
1038.03
AZN
3.14
P/S Ratio
ATHE
11.83
AZN
4.96
EV/EBITDA
ATHE
-2231.26
AZN
8.26

Profitability

Gross Margin
ATHE
97.66%
AZN
83.26%
Operating Margin
ATHE
-185.73%
AZN
24.11%
Profit Margin
ATHE
-223.35%
AZN
16.17%
ROE
ATHE
-43.23%
AZN
21.67%
ROA
ATHE
-28.09%
AZN
9.06%

Growth

Revenue Growth
ATHE
80.9%
AZN
12.0%
Earnings Growth
ATHE
--
AZN
78.0%

Financial Health

Debt/Equity
ATHE
0.0
AZN
0.71
Current Ratio
ATHE
12.98
AZN
0.88
Quick Ratio
ATHE
12.62
AZN
0.69

Dividends

Dividend Yield
ATHE
--
AZN
1.71%
Payout Ratio
ATHE
0.0%
AZN
51.99%

AI Verdict

ATHE BEARISH

The Advanced Deterministic Scorecard reveals a weak financial health profile with a Piotroski F-Score of 4/9, indicating borderline stability, and no available Altman Z-Score limits bankruptcy risk assessment. Despite strong revenue growth of 80.90% YoY and a pristine balance sheet with zero debt and a current ratio of 12.98, the company is deeply unprofitable with a profit margin of -223.35% and negative ROE of -43.23%. Valuation metrics are extreme, with a Price/Book of 1038.03 and a negative Forward P/E of -4.49, suggesting significant overvaluation relative to book and earnings. While insider sentiment is moderately positive at 40/100 and analysts project a high target price of $12.00, the lack of profitability, inconsistent cash flow data, and weak technical trend (0/100) raise serious concerns about sustainability.

Strengths
Exceptional revenue growth of 80.90% YoY, significantly above sector average of 23.74%
Zero debt with a Debt/Equity ratio of 0.00, indicating strong capital structure flexibility
Very high liquidity with Current Ratio of 12.98 and Quick Ratio of 12.62
Risks
Piotroski F-Score of 4/9 indicates weak financial health and limited profitability strength
Extremely high valuation: Price/Book of 1038.03 and negative Forward P/E suggest severe overvaluation
Deeply negative profitability: Profit margin of -223.35% and ROE of -43.23% signal ongoing losses
AZN NEUTRAL

AstraZeneca's deterministic health score is concerning with a Piotroski F-Score of 4/9, indicating marginal financial stability. While profitability metrics like ROE (21.67%) and gross margin (83.26%) are strong, the current price of $92.95 trades significantly above the Graham Number of $45.06, reflecting high growth expectations. Revenue and earnings growth are robust (12% and 78% YoY, respectively), but recent earnings surprises have been volatile, including a -25.9% miss in Q3 2025. Analysts maintain a strong_buy recommendation, though insider selling and weak technical trends (10/100) suggest caution near-term.

Strengths
Exceptional gross margin of 83.26% indicates strong pricing power and cost control
High ROE of 21.67% reflects efficient use of shareholder equity
Strong earnings growth of 78% YoY and solid revenue growth of 12% demonstrate momentum
Risks
Piotroski F-Score of 4/9 indicates weak financial health, particularly in liquidity and earnings consistency
Current Ratio of 0.88 and Quick Ratio of 0.69 signal potential short-term liquidity pressure
Earnings volatility with multiple recent misses, including a -25.9% surprise in Q3 2025

Compare Another Pair

ATHE vs AZN: Head-to-Head Comparison

This page compares Alterity Therapeutics Limited (ATHE) and AstraZeneca PLC (AZN) across key fundamental metrics including valuation ratios, profitability margins, growth rates, financial health indicators, and dividend metrics. Each metric highlights the better-performing stock so you can quickly identify relative strengths and weaknesses.

Our AI engine independently analyzes each company's financials, competitive position, and market conditions to produce a verdict (Bullish, Neutral, or Bearish) along with key strengths and risks. Use this comparison alongside your own research to make informed investment decisions.

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